Background One of the most important and often neglected physiological stimuli contributing
to the differentiation of vascular endothelial cells (ECs) into a blood-brain barrier (BBB) …

Resistance to chemotherapy is a major obstacle in cancer therapy. The main purpose of this
study is to evaluate the potential of a folate receptor-targeting nanoparticle to …

Commercial 68Ge/68Ga generators provide a means to produce positron emission
tomography agents on site without use of a cyclotron. This development has led to a rapid …

Resistance to chemotherapy remains a major obstacle in cancer therapy. This study aimed
to evaluate the molecular mechanism and efficacy of honokiol in inducing apoptosis and …

Background Cancer patients undergoing Doxorubicin (DOX) treatment are susceptible to
acute and chronic cardiac anomalies, including aberrant arrhythmias, ventricular …

The enantioselective oxidative coupling of 2-naphthols in water was established using
dinuclear vanadium (V/IV) catalysis with O 2 as the sole co-oxidant. In the vanadium …

Cancer chemotherapy has been used since the early 1950s and still remains one the major
therapeutic options for many malignant tumours. A major obstacle to successful cancer …

Lipophilic cationic technetium-99m-complexes are widely used for myocardial perfusion
imaging (MPI). However, inherent uncertainties in the supply chain of molybdenum-99, the …

Gallium-68 is a positron-emitting isotope that can be used in positron-emission tomography
imaging agents. Alzheimer's disease is associated with the formation of plaques in the brain …

Histopathological studies indicate that∼ 63% of pancreatic tumors express multidrug
resistance (MDR1) P-glycoprotein (Pgp) and its polymorphic variants. However, Pgp …