Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Current strategies for exosome cargo loading and targeting delivery

H Zeng, S Guo, X Ren, Z Wu, S Liu, X Yao - Cells, 2023 - mdpi.com
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …

Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

Exosomes: potential disease biomarkers and new therapeutic targets

MI Mosquera-Heredia, LC Morales, OM Vidal… - Biomedicines, 2021 - mdpi.com
Exosomes are extracellular vesicles released by cells, both constitutively and after cell
activation, and are present in different types of biological fluid. Exosomes are involved in the …

Bioengineered MSC-derived exosomes in skin wound repair and regeneration

H Zhao, Z Li, Y Wang, K Zhou, H Li, S Bi… - Frontiers in Cell and …, 2023 - frontiersin.org
Refractory skin defects such as pressure ulcers, diabetic ulcers, and vascular ulcers
represent a challenge for clinicians and researchers in many aspects. The treatment …

Exosomes as potential functional nanomaterials for tissue engineering

Y Yao, Y Jiang, J Song, R Wang, Z Li… - Advanced …, 2023 - Wiley Online Library
Exosomes are cell‐derived extracellular vesicles of 40–160 nm diameter, which carry
numerous biomolecules and transmit information between cells. They are used as functional …

[HTML][HTML] Advances in extracellular vesicle functionalization strategies for tissue regeneration

D Zheng, H Ruan, W Chen, Y Zhang, W Cui, H Chen… - Bioactive Materials, 2023 - Elsevier
Extracellular vesicles (EVs) are nano-scale vesicles derived by cell secretion with unique
advantages such as promoting cell proliferation, anti-inflammation, promoting blood vessels …

The exosome: a review of current therapeutic roles and capabilities in human reproduction

M Dimik, P Abeysinghe, J Logan, M Mitchell - Drug Delivery and …, 2023 - Springer
Abstract Exosomes are nano-vesicles (30–150 nm) which may be useful as therapeutic
delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the …

[HTML][HTML] Potential applications of using tissue-specific EVs in targeted therapy and vaccinology

TP Lehmann, M Golik, J Olejnik, M Łukaszewska… - Biomedicine & …, 2023 - Elsevier
Many cell types secrete spherical membrane bodies classified as extracellular vesicles
(EVs). EVs participate in intercellular communication and are present in body fluids …