Abstract Purpose of Review Once prostate cancer (PCa) bone metastases develop, the
prognosis dramatically declines. The precise mechanisms regulating bone metastasis …

Simple Summary S100 proteins are a group of calcium-binding proteins which have a
similar molecular mass and share similarities in their amino acid sequence. They are …

Prostate cancer (CaP) is the most diagnosed cancer in males and the second leading cause
of cancer deaths. Patients with localized tumors are generally curable. However, no curative …

S100A4 is a member of the large family of S100 proteins, exerting a broad range of
intracellular and extracellular functions that vary upon different cellular contexts. While …

Objective S100A4 is a DAMP protein. S100A4 is overexpressed in patients with systemic
sclerosis (SSc), and levels correlate with organ involvement and disease activity. S100A4 …

Angiogenesis plays the critical roles in promoting tumor progression, aggressiveness, and
metastasis. Although few studies have revealed some angiogenesis-related genes (ARGs) …

Abstract Background Although RANK‐LRANK interaction is essential for
osteoclastogenesis, the mechanisms by which cancer cells invade bone tissues and initiate …

Prostate cancer (CaP) is one of the most prevalent male malignancies, accounting for a
considerable number of annual mortalities. However, the prompt identification of early-stage …

Objectives: S100A4 is a Damage Associated Molecular Pattern (DAMP) protein. S100A4 is
overexpressed in systemic sclerosis (SSc) patients and levels correlate with organ …

The management and screening of prostate cancer (PC) is still the main problem in clinical
practice. In this study, we investigated the role of aggressiveness genetic markers for PC …