Ketamine was introduced into clinical practice in the 1960s and continues to be both
clinically useful and scientifically fascinating. With considerably diverse molecular targets …

The efficacy of the N-methyl-D-aspartate receptor antagonist ketamine as an analgesic
agent is still under debate, especially for indications such as chronic pain. To understand the …

Objectives We compared the tolerability and efficacy of intranasal subdissociative ketamine
to intranasal fentanyl for analgesia of children with acute traumatic pain and investigated the …

Background Ketamine has been suggested to be efficient in relieving chronic pain.
However, there is inconsistency across studies investigating the effect of ketamine for …

Background Subanesthetic doses of ketamine, an N-methyl-d-aspartate receptor antagonist
used as an adjuvant to opioid for the treatment of pain in adults with acute and chronic pain …

Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, has been postulated as an
adjuvant analgesic for preventing remifentanil-induced hyperalgesia after surgery. This …

BACKGROUND The administration of intravenous lidocaine during the peri-operative period
may improve pain management after paediatric surgery. OBJECTIVE To explore the …

Aims: Opioid-reduced anesthesia (ORA) was suggested to decrease morphine consumption
after adolescent idiopathic scoliosis (AIS) surgery and incidence of chronic pain. Materials & …

Muscle relaxation for tracheal intubation during paediatric... : European Journal of
Anaesthesiology | EJA Muscle relaxation for tracheal intubation during paediatric …

Background N-methyl-D-aspartate receptor activation has been implicated in the
pathobiology of inflammatory, nociceptive and neuropathic pain, opioid tolerance, opioid …