MicroRNA-155: a master regulator of inflammation

G Mahesh, R Biswas - Journal of Interferon & Cytokine Research, 2019 - liebertpub.com
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …

MicroRNAs: history, biogenesis, and their evolving role in animal development and disease

M Bhaskaran, M Mohan - Veterinary pathology, 2014 - journals.sagepub.com
The discovery of microRNAs (miRNAs) in 1993 followed by developments and discoveries
in small RNA biology have redefined the biological landscape by significantly altering the …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Lipopolysaccharide facilitates immune escape of hepatocellular carcinoma cells via m6A modification of lncRNA MIR155HG to upregulate PD-L1 expression

L Peng, B Pan, X Zhang, Z Wang, J Qiu, X Wang… - Cell biology and …, 2022 - Springer
Recent studies have suggested that the initiation and progression of hepatocellular
carcinoma (HCC) are closely associated with lipopolysaccharide (LPS) of intestinal bacteria …

Physiological and pathological roles for microRNAs in the immune system

RM O'connell, DS Rao, AA Chaudhuri… - Nature Reviews …, 2010 - nature.com
Mammalian microRNAs (miRNAs) have recently been identified as important regulators of
gene expression, and they function by repressing specific target genes at the post …

Oncomirs—microRNAs with a role in cancer

A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …

Micro-RNA: The darkhorse of cancer

M Budakoti, AS Panwar, D Molpa, RK Singh… - Cellular signalling, 2021 - Elsevier
The discovery of micro RNAs (miRNA) in cancer has opened up new vistas for researchers
in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding …

Regulation of the MIR155 host gene in physiological and pathological processes

TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …

MicroRNA-155 is induced during the macrophage inflammatory response

RM O'Connell, KD Taganov… - Proceedings of the …, 2007 - National Acad Sciences
The mammalian inflammatory response to infection involves the induction of several
hundred genes, a process that must be carefully regulated to achieve pathogen clearance …

Requirement of bic/microRNA-155 for Normal Immune Function

A Rodriguez, E Vigorito, S Clare, MV Warren, P Couttet… - Science, 2007 - science.org
MicroRNAs are a class of small RNAs that are increasingly being recognized as important
regulators of gene expression. Although hundreds of microRNAs are present in the …