[HTML][HTML] Nanometer-scale views of visual cortex reveal anatomical features of primary cilia poised to detect synaptic spillover

CM Ott, R Torres, TS Kuan, A Kuan, JA Buchanan… - bioRxiv, 2023 - ncbi.nlm.nih.gov
A primary cilium is a thin membrane-bound extension off a cell surface that contains
receptors for perceiving and transmitting signals that modulate cell state and activity. While …

Deciphering vesicle-assisted transport mechanisms in cytoplasm to cilium trafficking

M Tingey, A Ruba, Z Jiang, W Yang - Frontiers in Cellular …, 2024 - frontiersin.org
The cilium, a pivotal organelle crucial for cell signaling and proper cell function, relies on
meticulous macromolecular transport from the cytoplasm for its formation and maintenance …

Ultrastructural differences impact cilia shape and external exposure across cell classes in the visual cortex

CM Ott, R Torres, TS Kuan, A Kuan, JA Buchanan… - Current Biology, 2024 - cell.com
A primary cilium is a membrane-bound extension from the cell surface that contains
receptors for perceiving and transmitting signals that modulate cell state and activity. Primary …

[HTML][HTML] Exploring Cellular Gateways: Unraveling the Secrets of Disordered Proteins within Live Nuclear Pores

W Yu, M Tingey, JM Kelich, Y Li, J Yu, SL Junod… - Research …, 2024 - ncbi.nlm.nih.gov
Understanding the spatial organization of nucleoporins (Nups) with intrinsically disordered
domains within the nuclear pore complex (NPC) is crucial for deciphering eukaryotic …

[图书][B] The Application of Single-Point Edge-Excitation Sub-Diffraction Microscopy for the Study of Macromolecular Transport

M Tingey - 2023 - search.proquest.com
The development of super-resolution microscopy made it possible to surpass the diffraction
limit of optical microscopy, enabling researchers to gain a nanometer scale understanding of …