Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Emerging Burden

S Batool, K Morton Cuthrell, N Tzenios… - … Research Journal of …, 2022 - publish7promo.com
Liver is the largest solid organ in the body that performs over 100 functions. It removes the
toxins and waste products from the blood stream, maintains healthy blood sugar levels …

Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2019 - Elsevier
The obesity epidemic is closely associated with the rising prevalence and severity of
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …

Epidemiology of hepatocellular carcinoma and intrahepatic cholangiocarcinoma

NN Massarweh, HB El-Serag - Cancer control, 2017 - journals.sagepub.com
Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most
frequently occurring types of primary liver cancer and together are among the most common …

Evidence-based diagnosis, staging, and treatment of patients with hepatocellular carcinoma

J Bruix, M Reig, M Sherman - Gastroenterology, 2016 - Elsevier
Evidence-based management of patients with hepatocellular carcinoma (HCC) is key to
their optimal care. For individuals at risk for HCC, surveillance usually involves …

Diagnosis and staging of hepatocellular carcinoma (HCC): current guidelines

C Ayuso, J Rimola, R Vilana, M Burrel, A Darnell… - European journal of …, 2018 - Elsevier
One of the key strategies to improve the prognosis of HCC, beside prevention, is to diagnose
the tumor in early stages, when the patient is asymptomatic and the liver function is …

Liver transplantation for hepatocellular carcinoma: outcomes and novel surgical approaches

G Sapisochin, J Bruix - Nature reviews Gastroenterology & hepatology, 2017 - nature.com
Liver transplantation for hepatocellular carcinoma (HCC) is the best treatment option for
patients with early-stage tumours and accounts for∼ 20–40% of all liver transplantations …

[PDF][PDF] World‐wide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma

C de Martel, D Maucort‐Boulch, M Plummer… - …, 2015 - Wiley Online Library
Hepatitis B virus (HBV) and hepatitis C virus (HCV) are major causes of hepatocellular
carcinoma (HCC). In order to assess the relative contribution of HBV and HCV to HCC …

Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells

S Wan, E Zhao, I Kryczek, L Vatan, A Sadovskaya… - Gastroenterology, 2014 - Elsevier
Background & Aims Cancer stem cells (CSCs) can contribute to hepatocellular carcinoma
(HCC) progression and recurrence after therapy. The presence of tumor-associated …

Early detection, curative treatment, and survival rates for hepatocellular carcinoma surveillance in patients with cirrhosis: a meta-analysis

AG Singal, A Pillai, J Tiro - PLoS medicine, 2014 - journals.plos.org
Background Surveillance for hepatocellular carcinoma (HCC) has level I evidence among
patients with hepatitis B but only level II evidence in patients with cirrhosis. This lack of …

Trends in burden of cirrhosis and hepatocellular carcinoma by underlying liver disease in US veterans, 2001–2013

LA Beste, SL Leipertz, PK Green, JA Dominitz, D Ross… - Gastroenterology, 2015 - Elsevier
Background & Aims Cirrhosis and hepatocellular carcinoma (HCC) are predicted to increase
in the United States but the accuracy of prior forecasts and the contributions from various …