Much has been learned since the early 1960s about histone post-translational modifications
(PTMs) and how they affect DNA-templated processes at the molecular level. This …

Inherited epigenetic information has been observed to regulate a variety of complex
organismal phenotypes across diverse taxa of life. This continually expanding body of …

Highlights•Examples of transgenerational epigenetic inheritance of brain related
phenotypes.•Overview of putative molecular carriers of non-genetic information are …

Maternal stress can have long-lasting epigenetic effects on offspring. To examine how
epigenetic changes are triggered by stress, we examined the effects of activating the …

Gametogenesis produces the only cell type within a metazoan that contributes both genetic
and epigenetic information to the offspring. Extensive epigenetic dynamics are required to …

Paternal epigenetic inheritance is gaining attention for its growing medical relevance.
However, the form in which paternal epigenetic information is transmitted to offspring and …

Maternally synthesized products play critical roles in the development of offspring. A premier
example is the Caenorhabditis elegans H3K36 methyltransferase MES-4, which is essential …

Adult stem cells undergo asymmetric cell divisions to produce 2 daughter cells with distinct
cell fates: one capable of self-renewal and the other committed for differentiation …

The use of antibiotics in animal feeding has been banned in many countries because of
increasing concerns about the development of bacterial resistance to antibiotics and …

Mental illness remains the greatest chronic health burden globally with few in-roads having
been made despite significant advances in genomic knowledge in recent decades. The field …