Recombinant mucin biotechnology and engineering

S Park, JCH Kuo, HL Reesink, MJ Paszek - Advanced drug delivery reviews, 2023 - Elsevier
Mucins represent a largely untapped class of polymeric building block for biomaterials,
therapeutics, and other biotechnology. Because the mucin polymer backbone is genetically …

Mucins as potential biomarkers for early detection of cancer

SK Gautam, P Khan, G Natarajan, P Atri, A Aithal… - Cancers, 2023 - mdpi.com
Simple Summary Early cancer detection is a challenge in treating cancer patients.
Remarkably, carcinomas of the breast, lung, liver, pancreas, ovary, and colon contribute to …

Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy

A Quesnel, N Coles, C Angione, P Dey, TM Polvikoski… - Bmc Cancer, 2023 - Springer
Background Gliomas are the most common brain tumours with the high-grade glioblastoma
representing the most aggressive and lethal form. Currently, there is a lack of specific glioma …

Deciphering cellular and molecular mechanism of MUC13 mucin involved in cancer cell plasticity and drug resistance

S Malik, M Sikander, M Wahid, A Dhasmana… - Cancer and Metastasis …, 2024 - Springer
There has been a surge of interest in recent years in understanding the intricate
mechanisms underlying cancer progression and treatment resistance. One molecule that …

Development of human lung induction models for air pollutants' toxicity assessment

S Liu, R Yang, Y Chen, X Zhao, S Chen… - Environmental …, 2021 - ACS Publications
There is an urgent need for reliable and effective models to study air pollution health effects
on human lungs. Here, we report the utilization of human pluripotent stem cell (hPSC) …

Biomarkers in the management of lung cancer: changing the practice of thoracic oncology

B Melichar - Clinical Chemistry and Laboratory Medicine (CCLM), 2023 - degruyter.com
Lung cancer currently represents a leading cause of cancer death. Substantial progress
achieved in the medical therapy of lung cancer during the last decade has been associated …

MUC13 promotes the development of esophageal cancer by upregulating the expression of o-glycan process-related molecules

Y Han, G Chen, S Liu, G Zhou, X Xu, H Zhang, Z Li… - Discover Oncology, 2023 - Springer
Background Esophageal cancer is one of the most common malignant tumors in the world,
which is characterized by poor prognosis, aggressiveness, and poor survival. Mucin 13 …

Mucin 13 (MUC13) as a candidate biomarker for ovarian cancer detection: potential to complement CA125 in detecting non-serous subtypes

AH Ren, PS Filippou, A Soosaipillai… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Ovarian cancer is the most lethal gynecological malignancy in developed
countries. One of the key associations with the high mortality rate is diagnosis at late stages …

Diagnostic efficacy of combining diffusion‐weighted magnetic resonance imaging with serum Mucin 1, Mucin 13, and Mucin 16 in distinguishing borderline from …

XT Wen, HF Qiu, LL Ying, M Huang… - Asia‐Pacific Journal …, 2024 - Wiley Online Library
Aims To enhance ovarian tumor diagnosis beyond conventional methods, this study
explored combining diffusion‐weighted magnetic resonance imaging (DWI‐MRI) and serum …

Breaking the mucin barrier: a new affinity chromatography-mass spectrometry approach to unveil potential cell markers and pathways altered in Pseudomyxoma …

A Romero-Ruiz, M Granados-Rodríguez… - Biological Procedures …, 2024 - Springer
Background Pseudomyxoma peritonei (PMP) is a rare peritoneal mucinous carcinomatosis
with largely unknown underlying molecular mechanisms. Cytoreductive surgery combined …