Hyperpolarized carbon 13 MRI (13C MRI) is a novel imaging approach that can
noninvasively probe tissue metabolism in both normal and pathologic tissues. The process …

Liver disease is a major health concern globally, with high morbidity and mor-tality rates.
Precise diagnosis and assessment are vital for guiding treatment approaches, predicting …

Nuclear spin hyperpolarization enables real-time observation of metabolism and
intermolecular interactions in vivo. 1-13C-pyruvate is the leading hyperpolarized tracer …

Hyperpolarization methods in magnetic resonance enhance the signals by several orders of
magnitude, opening new windows for real‐time investigations of dynamic processes in vitro …

Purpose This study aimed to develop and demonstrate the in vivo feasibility of a 3D stack‐of‐
spiral balanced steady‐state free precession (3D‐bSSFP) urea sequence, interleaved with a …

Solid tumors such as prostate cancer (PCa) commonly develop an acidic microenvironment
with pH 6.5–7.2, owing to heterogeneous perfusion, high metabolic activity, and rapid cell …

Abstract Background Hyperpolarized (HP)[1-13C] pyruvate cardiovascular magnetic
resonance (CMR) imaging can visualize the uptake and intracellular conversion of [1-13C] …

We introduce a method for nondestructive quantification of nuclear spin polarization, of
relevance to hyperpolarized spin tracers widely used in magnetic resonance from …

Tumour metabolism can be imaged with a novel imaging technique termed hyperpolarised
carbon-13 (13 C)-MRI using probes, ie, endogenously found molecules that are labeled with …

Hyperpolarized carbon‐13 magnetic resonance imaging (HP 13C MRI) is a recently
translated metabolic imaging technique. With dissolution dynamic nuclear polarization (d …