Mycobacterium tuberculosis survives in antigen-presenting cells (APCs) such as macrophages and dendritic cells. APCs present antigens in association with major …
Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro- inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be …
K Sakamoto - Veterinary pathology, 2012 - journals.sagepub.com
Mycobacterium tuberculosis is an old enemy of the human race, with evidence of infection observed as early as 5000 years ago. Although more host-restricted than Mycobacterium …
Asthma pathogenesis is focused around conducting airways. The reasons for this focus have been unclear because it has not been possible to track the sites and timing of antigen …
GM Winslow, A Cooper, W Reiley… - Immunological …, 2008 - Wiley Online Library
Tuberculosis (TB) has plagued mankind for millennia yet is classified as an emerging infectious disease, because its prevalence in the human population continues to increase …
IR Humphreys, GR Stewart, DJ Turner, J Patel… - Microbes and …, 2006 - Elsevier
The ability of mycobacteria to disseminate from the initial site of infection has an important role in immune priming and in the seeding of disease in multiple organs. To study this …
The innate response plays a crucial role in the protection against tuberculosis development. Moreover, the initial steps that drive the host-pathogen interaction following Mycobacterium …
Dendritic cells (DC) have been shown to phagocytose and kill Cryptococcus neoformans in vitro and are believed to be important for inducing protective immunity against this organism …
Macrophage receptor with collagenous structure (MARCO) has an important role in the phagocytosis of Mycobacterium tuberculosis (M. tuberculosis). We hypothesized that …