Polymersomes

DE Discher, F Ahmed - Annu. Rev. Biomed. Eng., 2006 - annualreviews.org
Polymersomes are self-assembled polymer shells composed of block copolymer
amphiphiles. These synthetic amphiphiles have amphiphilicity similar to lipids, but they have …

Peptide self-assembly for nanomaterials: the old new kid on the block

E De Santis, MG Ryadnov - Chemical Society Reviews, 2015 - pubs.rsc.org
Peptide self-assembly is an increasingly attractive tool for nanomaterials. Perfected in
biology peptide self-assembling systems have impacted on nearly any conceivable …

Polymer architecture and drug delivery

LY Qiu, YH Bae - Pharmaceutical research, 2006 - Springer
Polymers occupy a major portion of materials used for controlled release formulations and
drug-targeting systems because this class of materials presents seemingly endless diversity …

Self-porating polymersomes of PEG–PLA and PEG–PCL: hydrolysis-triggered controlled release vesicles

F Ahmed, DE Discher - Journal of controlled release, 2004 - Elsevier
Controlled release polymer vesicles are prepared using hydrolysable diblock copolymers of
polyethyleneglycol–poly-l-lactic acid (PEG–PLA) or polyethyleneglycol–polycaprolactone …

Polymeric vesicles in biomedical applications

RP Brinkhuis, FPJT Rutjes, JCM van Hest - Polymer Chemistry, 2011 - pubs.rsc.org
Polymeric vesicles, or polymersomes, are nano-to micrometre sized polymeric capsules with
a bilayered membrane. Applications of these vesicles are foreseen in nanomedicine, in vivo …

Polymer vesicles in vivo: correlations with PEG molecular weight

PJ Photos, L Bacakova, B Discher, FS Bates… - Journal of Controlled …, 2003 - Elsevier
PEG-modified lipid vesicles have already shown considerable utility in delaying vesicle
clearance from the circulation. They are, however, limited in their ability to stably integrate …

[HTML][HTML] Block copolymer vesicles—using concepts from polymer chemistry to mimic biomembranes

K Kita-Tokarczyk, J Grumelard, T Haefele, W Meier - Polymer, 2005 - Elsevier
Owing to the increasing interest in self-assembled structures from block copolymer
materials, we present here a review of recent literature concerning amphiphilic block …

[PDF][PDF] Cell adhesion on artificial materials for tissue engineering

L Bačáková, E Filová, F Rypáček, V Švorčík, V Starý - Physiol Res, 2004 - researchgate.net
Advanced interdisciplinary scientific field of tissue engineering has been developed to meet
increasing demand for safe, functional and easy available substitutes of irreversibly …

Polymersome carriers: from self-assembly to siRNA and protein therapeutics

DA Christian, S Cai, DM Bowen, Y Kim… - European Journal of …, 2009 - Elsevier
Polymersomes are polymer-based vesicular shells that form upon hydration of amphiphilic
block copolymers. These high molecular weight amphiphiles impart physicochemical …

Emerging applications of polymersomes in delivery: from molecular dynamics to shrinkage of tumors

DE Discher, V Ortiz, G Srinivas, ML Klein, Y Kim… - Progress in polymer …, 2007 - Elsevier
Polymersomes are self-assembled shells of amphiphilic block copolymers that are currently
being developed by many groups for fundamental insights into the nature of self-assembled …