Non-pharmacological therapies, such as physical activity interventions, are an appealing
alternative or add-on to current pharmacological treatment of cognitive symptoms in patients …

Alzheimer's disease (AD) is an aging-related neurological disorder characterized by
synaptic loss and dementia. Wnt/β-catenin signaling is an essential signal transduction …

Questions What is the effect of physical exercise on cognitive decline and behavioural
problems in people with mild cognitive impairment (MCI) or dementia? What is the effect of …

Background: Studies of physical exercise in patients with Alzheimer's disease (AD) are few
and results have been inconsistent. Objective: To assess the effects of a moderate-to-high …

Objective Physical activity can be an effective means of prevention and therapy of many
psychosomatic disorders. It can also have a significant impact on the quality of life of older …

Objective To evaluate the effect of aerobic exercise on cognitive function in people with mild
cognitive impairment (MCI). Design Systematic review and meta-analysis of aerobic …

It is widely accepted that the brain and the immune system continuously interact during
normal as well as pathological functioning. Human aging is commonly accompanied by low …

Early reviews identified over 20 risk factors associated with Alzheimer's disease (AD)
including age, familial inheritance, exposure to aluminium, traumatic brain injury (TBI), and …

Background: High blood pressure has been associated with an increased risk of developing
cognitive impairment. However, this relationship is unclear. This study aims to systematically …

From animal research, it is known that combining physical activity with sensory enrichment
has stronger and longer-lasting effects on the brain than either treatment alone. For humans …