L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion
chelation, scavenging of reactive oxygen and nitrogen species, erythropoiesis, and the …

The methods of donor heart preservation are aimed at minimizing graft dysfunction caused
by ischaemia–reperfusion injury (IRI) which inevitably occurs during the ex vivo transport …

Objective To provide recommendations for enhanced recovery after cardiac surgery
(ERACS) based on a multimodal perioperative medicine approach in adult cardiac surgery …

The aim of the article is to examine side effects of increased dietary intake of amino acids,
which are commonly used as a dietary supplement. In addition to toxicity, mutagenicity and …

Objective To compare outcomes of single (intervention group: del Nido [DN], and histamine–
tryptophan–ketoglutarate) versus multidose (control group) cardioplegia in the adult cardiac …

Objective del Nido solution (DNS) is a single-dose cardioplegia designed for pediatric use
proposed to offer superior myocardial protection in adults. However, few data support this …

Ischemia–reperfusion is a cascade of complex and interrelated pathological processes
underlying many human diseases, including such socially significant diseases as stroke …

A variety of cardioplegic solutions are being used widely today to arrest the heart during
coronary artery bypass grafting (CABG) and other cardiac operations. To minimize …

Objectives We conducted a prospective randomized controlled trial to compare del Nido
(DN) and histidine-tryptophan-ketoglutarate (HTK) cardioplegia solution in pediatric patients …

During cardiac surgery, myocardial protection is performed using diverse cardioplegic (CP)
solutions with and without the presence of blood. New CP formulations extend ischemic …