Atherosclerosis is a chronic inflammatory vascular disease and the predominant cause of
heart attack and ischemic stroke. Despite the well-known sexual dimorphism in the …

Stroke represents a massive public health problem. Carotid atherosclerosis plays a
fundamental part in the occurence of ischaemic stroke. European and US guidelines for …

Background Increasing evidence suggests that atherosclerotic plaque composition rather
than plaque size is linked to ischemic cardiovascular events, yet largescale population …

Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted for the period beginning March 2008 through …

Background and Purpose—MRI characterization of carotid plaque has been studied recently
as a potential tool to predict stroke caused by carotid atherosclerosis. We performed a …

The ACCF/AHA writing committee to create the 2011 Guideline on the Management of
Patients With Extracranial Carotid and Vertebral Artery Disease (ECVD) conducted a …

Calcification is a clinical marker of atherosclerosis. This review focuses on recent findings on
the association between calcification and plaque vulnerability. Calcified plaques have …

Today's concept of vulnerable plaque has evolved primarily from the early pioneering work
uncovering the pivotal role of plaque rupture and coronary thrombosis as the major cause of …

Objectives: The goal of this study was to identify histomorphologic characteristics of
atherosclerotic plaques and to determine the amenability of some of these components to be …