Electrospun nanofiber scaffold for vascular tissue engineering

AP Rickel, X Deng, D Engebretson, Z Hong - Materials Science and …, 2021 - Elsevier
Due to the prevalence of cardiovascular diseases, there is a large need for small diameter
vascular grafts that cannot be fulfilled using autologous vessels. Although medium to large …

[HTML][HTML] Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts

Y Zhuang, C Zhang, M Cheng, J Huang, Q Liu… - Bioactive Materials, 2021 - Elsevier
Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,
which even result in dysfunction and death. Vascular regeneration or artificial vascular graft …

Tissue repair and regeneration with endogenous stem cells

H Xia, X Li, W Gao, X Fu, RH Fang, L Zhang… - Nature Reviews …, 2018 - nature.com
In contrast to non-mammalian vertebrates, mammals and humans have limited innate
capacity for the self-regeneration of tissues and organs owing to differences in genetics …

Extracellular vesicles: potential roles in regenerative medicine

OG De Jong, BWM Van Balkom… - Frontiers in …, 2014 - frontiersin.org
Extracellular vesicles (EV) consist of exosomes, which are released upon fusion of the
multivesicular body with the cell membrane, and microvesicles, which are released directly …

In situ tissue regeneration through host stem cell recruitment

IK Ko, SJ Lee, A Atala, JJ Yoo - Experimental & molecular medicine, 2013 - nature.com
The field of tissue engineering has made steady progress in translating various tissue
applications. Although the classical tissue engineering strategy, which involves the use of …

Tissue‐engineered vascular grafts: emerging trends and technologies

P Gupta, BB Mandal - Advanced Functional Materials, 2021 - Wiley Online Library
Vascular tissue engineering has made prodigious progress in recent years by converging
multidisciplinary approaches. Latest technological advancements foster the development of …

A bioink blend for rotary 3D bioprinting tissue engineered small-diameter vascular constructs

S Freeman, R Ramos, PA Chando, L Zhou, K Reeser… - Acta biomaterialia, 2019 - Elsevier
Abstract 3D bioprinted vascular constructs have gained increased interest due to their
significant potential for creating customizable alternatives to autologous vessel grafts. In this …

Controlling protein adsorption through nanostructured polymeric surfaces

I Firkowska‐Boden, X Zhang… - Advanced healthcare …, 2018 - Wiley Online Library
The initial host response to healthcare materials' surfaces after implantation is the
adsorption of proteins from blood and interstitial fluids. This adsorbed protein layer …

Vascular tissue engineering: from in vitro to in situ

S Li, D Sengupta, S Chien - Wiley Interdisciplinary Reviews …, 2014 - Wiley Online Library
Blood vessels transport blood to deliver oxygen and nutrients. Vascular diseases such as
atherosclerosis may result in obstruction of blood vessels and tissue ischemia. These …

Successful endothelialization and remodeling of a cell-free small-diameter arterial graft in a large animal model

MT Koobatian, S Row, RJ Smith Jr, C Koenigsknecht… - Biomaterials, 2016 - Elsevier
The large number of coronary artery bypass procedures necessitates development of off-the-
shelf vascular grafts that do not require cell or tissue harvest from patients. However …