DNA Mechanics: From Single Stranded to Self-Assembled

L Yang, Q Li, Z Ge, C Fan, W Huang - Nano Letters, 2024 - ACS Publications
DNA encodes genetic information and forms various structural conformations with distinct
physical, chemical, and biological properties. Over the past 30 years, advancements in force …

Motility of an autonomous protein-based artificial motor that operates via a burnt-bridge principle

CS Korosec, IN Unksov, P Surendiran… - Nature …, 2024 - nature.com
Inspired by biology, great progress has been made in creating artificial molecular motors.
However, the dream of harnessing proteins–the building blocks selected by nature–to …

Strategies to Reduce Promoter-Independent Transcription of DNA Nanostructures and Strand Displacement Complexes

SW Schaffter, E Kengmana, J Fern, SR Byrne… - ACS Synthetic …, 2024 - ACS Publications
Bacteriophage RNA polymerases, in particular T7 RNA polymerase (RNAP), are well-
characterized and popular enzymes for many RNA applications in biotechnology both in …

From Brownian to deterministic motor movement in a DNA-based molecular rotor

F Rothfischer, M Vogt, E Kopperger, U Gerland… - Nano Letters, 2024 - ACS Publications
Molecular devices that have an anisotropic periodic potential landscape can be operated as
Brownian motors. When the potential landscape is cyclically switched with an external force …

Compliant DNA Origami Nanoactuators as Size‐Selective Nanopores

Z Yu, AV Baptist, SCM Reinhardt, E Bertosin… - Advanced …, 2024 - Wiley Online Library
Biological nanopores crucially control the import and export of biomolecules across lipid
membranes in cells. They have found widespread use in biophysics and biotechnology …

An emerging artificial nanomachine: a nanoengine with a reversible clutch

Z Fang, J Jiang, M Wu - Signal Transduction and Targeted Therapy, 2024 - nature.com
Recently, a paper published in Nature Nanotechnology, 1 describes a magnetically driven
spherical rotating nanomotor with a reversible clutch system, capable of precisely regulating …

NucleoCraft: The Art of Stimuli-Responsive Precision in DNA and RNA Bioengineering

L Yu, L Chen, D Satyabola, A Prasad, H Yan - BME frontiers, 2024 - spj.science.org
Recent advancements in DNA and RNA bioengineering have paved the way for developing
stimuli-responsive nanostructures with remarkable potential across various applications …

HUH Endonuclease: A Sequence-Specific fusion protein tag for precise DNA-Protein conjugate

J Du, Y Kong, Y Wen, E Shen, H Xing - Bioorganic Chemistry, 2024 - Elsevier
Synthetic DNA-protein conjugates have found widespread applications in diagnostics and
therapeutics, prompting a growing interest in developing chemical biology methodologies …

DNA-Based Molecular Machines: Controlling Mechanisms and Biosensing Applications

C Ma, S Li, Y Zeng, Y Lyu - Biosensors, 2024 - mdpi.com
The rise of DNA nanotechnology has driven the development of DNA-based molecular
machines, which are capable of performing specific operations and tasks at the nanoscale …

Precise construction of DNA origami‐based materials for functional regulation on biological interface

Y Wu, X Wu, R Tian, Y Wang, B Ding… - Smart …, 2024 - Wiley Online Library
Precise design and control of molecular self‐assembly as living creatures are exciting ideas
in the field of nanotechnology. Characterized with predesigned geometries and accurate …