[HTML][HTML] Aptamers against cancer drug resistance: Small fighters switching tactics in the face of defeat

M Sanati, AR Afshari, SS Ahmadi, P Kesharwani… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Discovering novel cancer therapies has attracted extreme interest in the last decade. In this
regard, multidrug resistance (MDR) to chemotherapies is a key challenge in cancer …

DNA-based nanomaterials as drug delivery platforms for increasing the effect of drugs in tumors

AN Shishparenok, VV Furman, DD Zhdanov - Cancers, 2023 - mdpi.com
Simple Summary The use of drugs based on nucleic acids is a promising direction in
antitumor therapy. Some modified oligonucleotide analogs, such as antisense …

Aptamer guided nanomedicine strategies in prostate cancer: Targeting and diagnosis

S Shahrukh, N Jain, S Shah, P Famta… - Journal of Drug Delivery …, 2023 - Elsevier
Prostate cancer (PCa) is the predominant cancer among men across the globe.
Conventional therapies available for PCa suffer from limitations such as lack of target …

Exploring the potential of aptamers in targeting neuroinflammation and neurodegenerative disorders: Opportunities and challenges

AHY Kong, AJ Wu, OKY Ho, MMK Leung… - International Journal of …, 2023 - mdpi.com
Neuroinflammation is the precursor for several neurodegenerative diseases (NDDs), such
as Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) …

Advances in aptamers-based applications in breast cancer: drug delivery, therapeutics, and diagnostics

T Gholikhani, S Kumar, H Valizadeh… - International Journal of …, 2022 - mdpi.com
Aptamers are synthetic single-stranded oligonucleotides (such as RNA and DNA) evolved in
vitro using Systematic Evolution of Ligands through Exponential enrichment (SELEX) …

Enhancing the efficiency of lung cancer cell capture using microfluidic dielectrophoresis and aptamer‐based surface modification

SH Lin, TC Su, SJ Huang, CP Jen - Electrophoresis, 2024 - Wiley Online Library
Metastasis remains a significant cause to cancer‐related mortality, underscoring the critical
need for early detection and analysis of circulating tumor cells (CTCs). This study presents a …

[HTML][HTML] Emerging frontiers in nanomedicine targeted therapy for prostate cancer

TA Adekiya, O Owoseni - Cancer Treatment and Research …, 2023 - Elsevier
Prostate cancer is a prevalent cancer in men, often treated with chemotherapy. However, it
tumor cells are clinically grows slowly and is heterogeneous, leading to treatment resistance …

An electrostatically conjugated-functional MNK1 aptamer reverts the intrinsic antitumor effect of polyethyleneimine-coated iron oxide nanoparticles in vivo in a human …

V Mulens-Arias, Y Portilla, S Pérez-Yagüe… - Cancer …, 2023 - Springer
Background Triple-negative breast cancer (TNBC) remains a difficult breast cancer subtype
to treat as it exhibits a particularly aggressive behavior. The dysregulation of distinct …

Advancements and Challenges in Aptamer-Based Therapeutics and Diagnostics Across Diverse Medical Domains: A Comprehensive Review

ASAA Agha, W Alshaer, T Aburjai - Jordan Journal of …, 2024 - jjournals.ju.edu.jo
Aptamers, which are single-stranded DNA or RNA molecules, are increasingly recognized
as important tools in diagnostics and therapeutics across various medical disciplines such …

Applications of nucleic acid aptamers in cancer diagnostics from the laboratory to the clinic

EM Kumar, S Enamala, R Dixit… - … for Point-of-Care …, 2023 - iopscience.iop.org
Applications of nucleic acid aptamers in cancer diagnostics from the laboratory to the clinic -
Book chapter - IOPscience This site uses cookies. By continuing to use this site you agree to …