DOI estimation through signal arrival time distribution: a theoretical description including proof of concept measurements

F Loignon-Houle, S Gundacker… - Physics in Medicine …, 2021 - iopscience.iop.org
The challenge to reach 10 ps coincidence time resolution (CTR) in time-of-flight positron
emission tomography (TOF-PET) is triggering major efforts worldwide, but timing …

Characterization of CsI (Tl) and LYSO (Ce) scintillator detectors by measurements and Monte Carlo simulations

I Mouhti, A Elanique, MY Messous, A Benahmed… - Applied Radiation and …, 2019 - Elsevier
In this study, we investigated the performance of two cuboid scintillation detectors: thallium-
activated cesium iodide [CsI (Tl)] and cerium-doped lutetium yttrium orthosilicate [LYSO …

Analytical model of DOI-induced time bias in ultra-fast scintillation detectors for TOF-PET

M Toussaint, F Loignon-Houle… - Physics in Medicine …, 2019 - iopscience.iop.org
In positron emission tomography (PET), long crystals (20 mm) are used to enhance
detection efficiency and increase scanner sensitivity. However, for fast time-of-flight (TOF) …

Enhancing etoposide aqueous solubility and anticancer activity with L-arginine

A Alsalhi, NJ Ayon, F Coulibaly… - ASSAY and Drug …, 2021 - liebertpub.com
It is hypothesized that L-arginine (ARG) can improve etoposide (VP-16) water solubility
while preserving its anticancer activity. Factorial design is used to identify conditions for …

Reflectivity quenching of ESR multilayer polymer film reflector in optically bonded scintillator arrays

F Loignon-Houle, CM Pepin, SA Charlebois… - Nuclear Instruments and …, 2017 - Elsevier
The 3M-ESR multilayer polymer film is a widely used reflector in scintillation detector arrays.
As specified in the datasheet and confirmed experimentally by measurements in air, it is …

Measuring the refractive index of scintillation crystal with a Mach-Zehnder interferometer

X Liu, J Long, Y Ding, Y Hu, Z Du, B Xu, D Deng - Optics Continuum, 2022 - opg.optica.org
The refractive index of the scintillation crystal is a key parameter in the design of Positron
Emission Tomography (PET) devices. However, existing methods to measure the refractive …

Experimental validation of a coincidence time resolution metric including depth-of-interaction bias for TOF-PET

F Loignon-Houle, M Toussaint, MS Lee… - Physics in Medicine …, 2020 - iopscience.iop.org
Abstract Depth-of-interaction (DOI) variability of annihilation photons is known to be a source
of coincidence time resolution (CTR) degradation for fast time-of-flight–positron emission …

Characterization of intrinsic radiation in LYSO scintillators using GEANT4 and SimSiPM simulations

OB Kolcu - Applied Radiation and Isotopes, 2025 - Elsevier
The intrinsic radiation spectra of LYSO scintillators are investigated through detailed
GEANT4 and SimSiPM simulations, focusing on how changes in configuration and size …

A new optical photon transport model for application to high aspect ratio scintillation pillars

A Moustafa, J Mattingly - Nuclear Instruments and Methods in Physics …, 2022 - Elsevier
A new Monte Carlo model of optical photon transport has been developed for application to
scintillation pillars with side surfaces modeled using their measured 3D topography. The …

[图书][B] Optimization of Optical Photon Transport Models for Application in High Aspect Ratio Scintillation Pillars

AM Moustafa - 2022 - search.proquest.com
High aspect ratio scintillation pillars are utilized in a wide range of position-sensitive
radiation detector applications. Validated models of scintillation light transport in these …