The immunomodulatory effects of lactoferrin and its derived peptides on NF‐κB signaling pathway: A systematic review and meta‐analysis
HA Yami, M Tahmoorespur… - Immunity …, 2023 - Wiley Online Library
Background Lactoferrin is a versatile protein with important modulatory functions in
inflammation and immune response. This glycoprotein can bind and sequester iron and …
inflammation and immune response. This glycoprotein can bind and sequester iron and …
Lactoferrin alleviates cyclophosphamide induced-nephropathy through suppressing the orchestration between Wnt4/β-catenin and ERK1/2/NF-κB signaling and …
OS Mohamed, NAA Baky, MM Sayed-Ahmed… - Life Sciences, 2023 - Elsevier
Aims Cyclophosphamide is an alkylating agent with vast arrays of therapeutic activity.
Currently, its medical use is limited due to its numerous adverse events, including …
Currently, its medical use is limited due to its numerous adverse events, including …
[HTML][HTML] The Novel Effect and Potential Mechanism of Lactoferrin on Organ Fibrosis Prevention
Y Yu, J Fang, Y Li, X Wang, J Zhang, J Wang, B Sun - Nutrients, 2025 - mdpi.com
Organ fibrosis is gradually becoming a human health and safety problem, and various
organs of the body are likely to develop fibrosis. The ultimate pathological feature of …
organs of the body are likely to develop fibrosis. The ultimate pathological feature of …
Pramipexole and Lactoferrin ameliorate Cyclophosphamide-Induced haemorrhagic cystitis via targeting Sphk1/S1P/MAPK, TLR-4/NF-κB, and NLRP3/caspase-1/IL-1β …
Background The use of cyclophosphamide (CP) as a chemotherapeutic agent is limited by
its major complication haemorrhagic cystitis (HC). Finding preventive, safe, and efficient …
its major complication haemorrhagic cystitis (HC). Finding preventive, safe, and efficient …
Lactoferrin averts neurological and behavioral impairments of thioacetamide-induced hepatic encephalopathy in rats via modulating HGMB1/TLR-4/MyD88/Nrf2 …
RM Essam, MA Saadawy, M Gamal, RM Abdelsalam… - …, 2023 - Elsevier
Hepatic encephalopathy (HE) is a life-threatening disease caused by acute or chronic liver
failure manifested by aberrant CNS changes. In the present study, we aimed to explore the …
failure manifested by aberrant CNS changes. In the present study, we aimed to explore the …
Extraction technology, components analysis and anti-inflammatory activity in vitro of total flavonoids extract from Artemisia anomala S. Moore
Y Shao, R Hong, B Li, A Wang, Y Chen, Y Wang, F Mo… - Fitoterapia, 2023 - Elsevier
Artemisia anomala S. Moore exerts many pharmacological activities, including the removing
of the blood stasis, relieving of the fever and analgesia, reducing the swelling and …
of the blood stasis, relieving of the fever and analgesia, reducing the swelling and …
Integrating network pharmacology and pharmacological evaluation to reveal the therapeutic effects and potential mechanism of S-allylmercapto-N-acetylcysteine on …
J Wang, H Yang, D Zheng, Y Sun, L An, G Li… - International …, 2023 - Elsevier
In this research, we sought to examine the effectiveness of S-allylmercapto-N-acetylcysteine
(ASSNAC) on LPS-provoked acute respiratory distress syndrome (ARDS) and its potential …
(ASSNAC) on LPS-provoked acute respiratory distress syndrome (ARDS) and its potential …
[HTML][HTML] Lactoferrin alleviates Western diet-induced cognitive impairment through the microbiome-gut-brain axis
Q He, LL Zhang, D Li, J Wu, YX Guo, J Fan… - Current Research in …, 2023 - Elsevier
Lactoferrin (Lf) has been shown to benefit cognitive function in several animal models. To
elucidate the underlying mechanisms, male C57BL/6J mice were randomly divided into the …
elucidate the underlying mechanisms, male C57BL/6J mice were randomly divided into the …
[HTML][HTML] The Role of the Gut-Lung Axis in COVID-19 Infections and Its Modulation to Improve Clinical Outcomes
J Chen, L Vitetta - Frontiers in Bioscience-Scholar, 2022 - imrpress.com
The main entry point of SARS-CoV-2 is the respiratory tract and as such immune defence in
this site determines if the virus will spill-over to the systemic circulation and circulate and …
this site determines if the virus will spill-over to the systemic circulation and circulate and …
Ovotransferrin exerts bidirectional immunomodulatory activities via TLR4‐mediated signal transduction pathways in RAW264. 7 cells
Z Ru, M Xu, G Zhu, Y Tu, Y Jiang… - Food Science & …, 2021 - Wiley Online Library
The immune regulation function of ovotransferrin (OVT) explored using the RAW264. 7 was
induced by lipopolysaccharide (LPS) as vitro model in this study. The results showed that …
induced by lipopolysaccharide (LPS) as vitro model in this study. The results showed that …