Prognostic biomarkers of cell proliferation in colorectal cancer (CRC): from immunohistochemistry to molecular biology techniques

A Kasprzak - Cancers, 2023 - mdpi.com
Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …

[HTML][HTML] PHD2 exerts anti-cancer and anti-inflammatory effects in colon cancer xenografts mice via attenuating NF-κB activity

L Wang, Z Niu, X Wang, Z Li, Y Liu, F Luo, X Yan - Life sciences, 2020 - Elsevier
Recent studies suggested that prolyl hydroxylase 2 (PHD2) functions as an important
regulator in vascular inflammation and Streptococcus pneumonia infection. However …

Kras mutations and p53 overexpression in pseudomyxoma peritonei: association with phenotype and prognosis

S Shetty, P Thomas, B Ramanan, P Sharma… - journal of surgical …, 2013 - Elsevier
BACKGROUND: Little information exists on Kras mutations and p53 overexpression in
pseudomyxoma peritonei (PMP). These genetic alterations are associated with poorer …

Association between Ki67 index and clinicopathological features in colorectal cancer

P Li, ZT Xiao, TA Braciak, QJ Ou, G Chen… - Oncology Research …, 2016 - karger.com
Background: Conflicting results have been reported about the association between the Ki67
labeling index (Ki67-Li) and clinical outcome in patients with colorectal cancer (CRC) …

Expression of CDX-2 and Ki-67 in different grades of colorectal adenocarcinomas

A Sen, S Mitra, RN Das, S Dasgupta… - Indian Journal of …, 2015 - journals.lww.com
Background: CDX2 is a caudal homeobox gene essential for intestinal differentiation and is
specifically expressed in colorectal adenocarcinomas. Its role in colorectal carcinogenesis is …

[HTML][HTML] Correlation of p53 overexpression with the clinicopathological prognostic factors in colorectal adenocarcinoma

C Akshatha, V Mysorekar, S Arundhathi… - Journal of clinical and …, 2016 - ncbi.nlm.nih.gov
Aim To establish a correlation between overexpression of p53 with the clinical features,
tumour histopathology and stage of Colorectal Carcinoma (CRC). Materials and Methods …

Prognostic value of combining E-cadherin, p53, Bcl-2 and Bcl-xL expression and survival in Tunisian colorectal adenocarcinoma patients

D Jamai, S Mekrezi, M Gharsallah, A Khabir… - Cellular and Molecular …, 2022 - cellmolbiol.org
Colorectal cancer (CRC) is a common health issue worldwide with an extremely low survival
rate after relapse. This study aims to evaluate the immunohistochemical expression of p53 …

Histopathological and immunohistochemical evaluation of CDX2 and Ki67 in colorectal lesions with their expression pattern in different histologic variants, Grade, and …

J Nayak, P Mohanty, A Lenka, N Sahoo… - Journal of Microscopy …, 2021 - journals.lww.com
Background: A variety of colorectal lesions are surgically treated encompassing both benign
and malignant polyps and colorectal cancer (CRC). CRC is the third most common cause of …

[PDF][PDF] Immunohistochemical expression of p53 and Bcl-2 in colorectal adenomas and carcinomas using automated cellular imaging system

Q BAN, ALI HUSAM, H ALAA - 2012 - sid.ir
Background & Objective: The current approaches to reduce the risk of colorectal carcinoma
are through the detection and removal of the precursor lesion” adenomatous polyps”. The …

Cyclin-dependent kinase inhibitor p21 and proliferative marker ki67 in colonic carcinoma

S Kumar, N Singh, SP Kataria, S Kandoi… - Journal of Cancer …, 2022 - journals.lww.com
Objective: Tumor grade employed for colorectal cancer has long been based on the degree
of differentiation, which is difficult to judge objectively. The aim of this study was to assess …