α-crystallin is a major protein found in the mammalian eye lens that works as a molecular
chaperone by preventing the aggregation of proteins and providing tolerance to stress in the …

The eye lens is a transparent, ellipsoid tissue in the anterior chamber that is required for the
fine focusing of light onto the retina to transmit a clear image. The focusing function of the …

Several discoveries show that with age and cataract formation, β-crystallin binds with the
lens membrane or associates with other lens proteins, which bind with the fiber cell plasma …

Purpose This research aims to probe the interaction of α-crystallin with a model of human,
porcine, and mouse lens-lipid membranes. Methods Cholesterol/model of human lens-lipid …

Experimental evidence shows that the eye lens loses its elasticity dramatically with age. It
has also been reported that the cholesterol (Chol) content in the eye lens fiber cell plasma …

Several studies reported that α-crystallin concentrations in the eye lens cytoplasm decrease
with a corresponding increase in membrane-bound α-crystallin with age and cataracts. The …

α-crystallin-membrane association increases with age and cataracts, with the primary
association site of α-crystallin being phospholipids. However, it is unclear if phospholipids' …

The lens of the eye loses elasticity with age, while α-crystallin association with the lens
membrane increases with age. It is unclear whether there is any correlation between α …

α-Crystallin (αABc) is a major protein comprised of αA-crystallin (αAc) and αB-crystallin (αBc)
that is found in the human eye lens and works as a molecular chaperone by preventing the …

Eye lens α-crystallin has been shown to become increasingly membrane-bound with age
and cataract formation; however, to our knowledge, no studies have investigated the …