Paracetamol: overdose-induced oxidative stress toxicity, metabolism, and protective effects of various compounds in vivo and in vitro

X Wang, Q Wu, A Liu, A Anadón… - Drug metabolism …, 2017 - Taylor & Francis
Paracetamol (APAP) is one of the most widely used and popular over-the-counter analgesic
and antipyretic drugs in the world when used at therapeutic doses. APAP overdose can …

[PDF][PDF] Peltophorum pterocarpum: chemical and pharmacological aspects

SK Jash, RK Singh, S Majhi, A Sarkar… - Int J Pharm Sci …, 2014 - researchgate.net
The present work offers a review addressing the detailed chemistry and pharmacology of
Peltophorum pterocarpum (belonging to Fabaceae family) regarded as one of the most …

Evaluation of Hepatoprotective Activity of Adansonia digitata Extract on Acetaminophen‐Induced Hepatotoxicity in Rats

A Hanafy, HM Aldawsari, JM Badr… - Evidence‐Based …, 2016 - Wiley Online Library
The methanol extract of the fruit pulp of Adansonia digitata L.(Malvaceae) was examined for
its hepatoprotective activity against liver damage induced by acetaminophen in rats. The …

Design and optimization of self-nanoemulsifying delivery system to enhance quercetin hepatoprotective activity in paracetamol-induced hepatotoxicity

OAA Ahmed, SM Badr-Eldin, MK Tawfik… - Journal of …, 2014 - Elsevier
The present study aimed to develop optimized quercetin (QT)-loaded self-nanoemulsifying
drug delivery system (SNEDDS) that offers protective effect against liver damage. Solubility …

[PDF][PDF] Morinda lucida attenuates acetaminophen-induced oxidative damage and hepatotoxicity in rats

MO Didunyemi, BO Adetuyi… - Journal of Biomedical …, 2019 - researchgate.net
The propanol and aqueous leaves extracts of Morinda lucida were evaluated for their
hepatoprotective potential on oxidative stress and acute liver damage induced by …

[PDF][PDF] Hepatoprotective effect of olive oil and camel milk on acetaminophen-induced liver toxicity in mice

MAB Ibrahim, FA Wani, S Rahiman - International Journal of Medical …, 2017 - academia.edu
Background: Acetaminophen overdose is a major cause of drug-induced liver failure.
Objective: To investigate the hepatoprotective effects of Extra Virgin Olive Oil (EVOO) and …

Inhibition of phospholipase A2, platelet aggregation and egg albumin induced rat paw oedema as anti-inflammatory effect of Peltophorun pterocarpus stem-bark

OC Enechi, ES Okeke, OE Awoh, CO Okoye… - Clinical …, 2021 - Springer
Background Most medicinal plants presently employed in traditional medicine are used
without scientific evidence, thereby suggesting a need to explore efficient and reliable …

Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts

S Donkor, C Larbie, G Komlaga… - Journal of …, 2020 - Wiley Online Library
Liver disease is a major health problem and its treatment is costly in most developing
countries with attendant adverse effects. This study aimed at determining the acute …

[PDF][PDF] Hepatoprotective and antioxidant effects of Cichorium endivia L. leaves extract against acetaminophen toxicity on rats

M Marzouk, AA Sayed, AM Soliman - J. Med. Med. Sci, 2011 - researchgate.net
The current study was carried out to elucidate the effect of hydroalcoholic extract of
Cichorium endivia L. leaves (HCE) against acetaminophen-induced oxidative stress and …

Chemical Constituents of the Leaves of Peltophorum pterocarpum and Their Bioactivity

YC Li, PC Kuo, ML Yang, TY Chen, TL Hwang… - Molecules, 2019 - mdpi.com
Two new sesquiterpenoids peltopterins A and B (compounds 1 and 2) and fifty-two known
compounds were isolated from the methanol extract of P. pterocarpum and their chemical …