High performance liquid chromatography: a versatile tool for assaying antiepileptic drugs in biological matrices

KFM Opuni, JA Boadu, SK Amponsah… - Journal of Chromatography …, 2021 - Elsevier
Epilepsy is a recurrent long-term illness occurring in approximately 1.0% of the world's
population. There are currently about 29 approved antiepileptic drugs for the management …

A critical review of microextraction by packed sorbent as a sample preparation approach in drug bioanalysis

G Alves, M Rodrigues, A Fortuna, A Falcão, J Queiroz - Bioanalysis, 2013 - Taylor & Francis
Sample preparation is widely accepted as the most labor-intensive and error-prone part of
the bioanalytical process. The recent advances in this field have been focused on the …

First HPLC–UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10, 11-epoxide, 10, 11 …

A Serralheiro, G Alves, A Fortuna, M Rocha… - … of Chromatography B, 2013 - Elsevier
A sensitive and fast high-performance liquid chromatographic method coupled with
ultraviolet detection is herein reported for the simultaneous determination of human plasma …

Development and validation of an HPLC-UV method for the simultaneous quantification of carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main …

A Fortuna, J Sousa, G Alves, A Falcão… - Analytical and …, 2010 - Springer
For the first time, a simple, selective and accurate high-performance liquid chromatography
method with ultraviolet detection was developed and validated to quantify simultaneously …

Drug monitoring: simultaneous analysis of lamotrigine, oxcarbazepine, 10-hydroxycarbazepine, and zonisamide by HPLC-UV and a rapid GC method using a …

E Greiner-Sosanko, S Giannoutsos… - Journal of …, 2007 - academic.oup.com
A high-performance liquid chromatography (HPLC) assay using UV detection is described
for the simultaneous measurement of the newer generation anti-epileptic medications …

Liquid chromatographic analysis of oxcarbazepine and its metabolites in plasma and saliva after a novel microextraction by packed sorbent procedure

MA Saracino, K Tallarico, MA Raggi - Analytica chimica acta, 2010 - Elsevier
A rapid and reliable analytical method suitable for the simultaneous determination of the
antiepileptic drug, oxcarbazepine and its metabolites in human plasma and saliva by means …

Antipsychotic and antiepileptic drugs in bipolar disorder: the importance of therapeutic drug monitoring

A Musenga, MA Saracino, G Sani… - Current medicinal …, 2009 - ingentaconnect.com
Bipolar disorder (BD) is a long-term illness with mood swings which are characterized by
recurrent episodes of mania/hypomania and depression, with variable interpolations of …

Dendrimer conjugates

JR Baker Jr, XM Cheng, AFL Van Der Spek… - US Patent …, 2014 - Google Patents
2010-03-01 Assigned to THE REGENTS OF THE UNIVERSITY OF MICHIGAN reassignment
THE REGENTS OF THE UNIVERSITY OF MICHIGAN ASSIGNMENT OF ASSIGNORS …

Sensitive inexpensive HPLC determination of four antiepileptic drugs in human plasma: application to PK studies

FA Ibrahim, AF El-Yazbi, MA Barary, MM Wagih - Bioanalysis, 2016 - Taylor & Francis
Aim: Recently, polytherapy regimen has been introduced for the treatment of epileptic
patients for better seizure control with lesser side effects and better control of multiple …

Does oxcarbazepine warrant therapeutic drug monitoring? A critical review

P Bring, MHH Ensom - Clinical pharmacokinetics, 2008 - Springer
Oxcarbazepine, the 10-keto analogue of carbamazepine, is approved for the treatment of
partial seizures or generalized tonic-clonic seizures. The primary metabolite of …