Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal

A Ayala, MF Muñoz, S Argüelles - Oxidative medicine and …, 2014 - Wiley Online Library
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

Oxidatively Generated Damage to Cellular DNA by UVB and UVA Radiation,

J Cadet, T Douki, JL Ravanat - Photochemistry and …, 2015 - Wiley Online Library
This review article focuses on a critical survey of the main available information on the UVB
and UVA oxidative reactions to cellular DNA as the result of direct interactions of UV …

Life and death: metabolic rate, membrane composition, and life span of animals

AJ Hulbert, R Pamplona, R Buffenstein… - Physiological …, 2007 - journals.physiology.org
Maximum life span differences among animal species exceed life span variation achieved
by experimental manipulation by orders of magnitude. The differences in the characteristic …

Human biomonitoring: state of the art

J Angerer, U Ewers, M Wilhelm - International journal of hygiene and …, 2007 - Elsevier
Human biomonitoring (HBM) of dose and biochemical effect nowadays has tremendous
utility providing an efficient and cost effective means of measuring human exposure to …

Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates

P Lonkar, PC Dedon - International journal of cancer, 2011 - Wiley Online Library
Chronic inflammation has long been recognized as a risk factor for many human cancers.
One mechanistic link between inflammation and cancer involves the generation of nitric …

[HTML][HTML] Biomarkers of nucleic acid oxidation–A summary state-of-the-art

MR Chao, MD Evans, CW Hu, Y Ji, P Møller, P Rossner… - Redox Biology, 2021 - Elsevier
Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …

Measurement and meaning of oxidatively modified DNA lesions in urine

MS Cooke, R Olinski, S Loft… - … Biomarkers & Prevention, 2008 - AACR
Background: Oxidatively generated damage to DNA has been implicated in the
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …

Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts

S Liu, Y Wang - Chemical Society Reviews, 2015 - pubs.rsc.org
Exogenous and endogenous sources of chemical species can react, directly or after
metabolic activation, with DNA to yield DNA adducts. If not repaired, DNA adducts may …

The chemical toxicology of 2-deoxyribose oxidation in DNA

PC Dedon - Chemical research in toxicology, 2008 - ACS Publications
Damage to DNA and RNA caused by oxidative mechanisms has been well-studied for its
potential role in the development of human disease. Only recently, though, have we begun …

Lipid peroxidation: Reactive carbonyl species, protein/DNA adducts, and signaling switches in oxidative stress and cancer

NT Moldogazieva, SP Zavadskiy, DV Astakhov… - Biochemical and …, 2023 - Elsevier
Under the exposure of lipids to reactive oxygen species (ROS), lipid peroxidation proceeds
non-enzymatically and generates an extremely heterogeneous mixture of reactive carbonyl …