Adaptive behaviour requires the ability to focus on a task and protect it from distraction
(cognitive stability) and to rapidly switch tasks when circumstances change (cognitive …

The primate prefrontal cortex (PFC) subserves our highest order cognitive operations, and
yet is tremendously dependent on a precise neurochemical environment for proper …

We describe an ambitious ongoing study that has been strongly influenced and inspired by
Don Stuss's career-long efforts to identify key cognitive processes that characterize …

Reinforcement learning and working memory are two core processes of human cognition
and are often considered cognitively, neuroscientifically, and algorithmically distinct. Here …

Bromocriptine is a sympatholytic dopamine D2 receptor agonist with remarkable
bioactivities. It has been used clinically as a prescription drug for more than 30 years to treat …

Computational models and neurophysiological data propose that a 'gating mechanism'
coordinates distractor-resistant maintenance and flexible updating of working memory …

The contents of working memory must be maintained in the face of distraction, but updated
when appropriate. To manage these competing demands of stability and flexibility …

There is increasing evidence that the left lateral frontal cortex is hierarchically organized
such that higher-order regions have an asymmetric top–down influence over lower order …

In rodents and nonhuman primates, sex hormones are powerful modulators of dopamine
(DA) neurotransmission. Yet less is known about hormonal regulation of the DA system in …

Introduction Caffeine is frequently consumed to boost goal-directed attention. These
procognitive effects may occur due to the adenosine-mediated enhancement of …