Protein kinase D (PKD) is a family of serine/threonine protein kinases operating in the
signaling network of the second messenger diacylglycerol. The three family members …

Protein kinase D is a family of evolutionarily conserved serine/threonine kinases that
belongs to the Ca++/Calmodulin-dependent kinase superfamily. Signal transduction …

The Golgi Complex is the central hub in the endomembrane system and serves not only as a
biosynthetic and processing center but also as a trafficking and sorting station for …

Prostate cancer (PCa) is one of the most common malignancies found in males. The
development of PCa involves several mutations in prostate epithelial cells, usually linked to …

Extensive research has led to the firm conclusion that antioxidants protect cells from damage
caused by oxidative stress and its associated pathological conditions including …

Cardiac fibrosis is an important pathological feature of cardiac remodeling in heart diseases.
The molecular mechanisms of cardiac fibrosis are unknown. Histone deacetylases (HDACs) …

Abstract Protein kinase D1 (PKD1) is a serine/threonine kinase that belongs to the
calcium/calmodulin-dependent kinase family, and is involved in multiple mechanisms …

The protein kinase D (PKD) family is a family of serine-threonine kinases that are members
of the calcium/calmodulin-dependent kinase (CaMK) superfamily. PKDs have been …

Posttranslational modifications including histone methylation regulate gene transcription
through directly affecting the structure of chromatin. Trimethylation of histone H3K27 …

The programmed death-ligand 1 (PD-L1), by binding to PD-1 on the surface of immune cells,
activates a major immune checkpoint pathway. Elevated expression of PD-L1 in tumor cells …