Recent progress in nanostructured smart drug delivery systems for cancer therapy: a review

MI Khan, MI Hossain, MK Hossain… - ACS Applied Bio …, 2022 - ACS Publications
Traditional treatment approaches for cancer involve intravenous chemotherapy or other
forms of drug delivery. These therapeutic measures suffer from several limitations such as …

Magnetic iron oxide nanogels for combined hyperthermia and drug delivery

S Patri, NTK Thanh, N Kamaly - Nanoscale, 2024 - pubs.rsc.org
Hyperthermia and chemotherapy represent established modalities for cancer treatments.
However, hyperthermia can be invasive, while chemotherapy drugs often have severe side …

Synthesis and characterization of silica nanoparticles from rice ashes coated with chitosan/cancer cell membrane for hepatocellular cancer treatment

MJC Espinoza, KS Lin, MT Weng, SC Kunene… - International Journal of …, 2023 - Elsevier
Dual pH-sensitive smart nanocarriers based on silica nanoparticles (SNPs) extracted from
rice husk ashes (RHAs) to effectively inhibit liver cancer cell proliferation were investigated …

Magnetic boron nitride nanosheets-based on pH-responsive smart nanocarriers for the delivery of doxorubicin for liver cancer treatment

MJC Espinoza, KS Lin, MT Weng, SC Kunene… - Colloids and Surfaces B …, 2023 - Elsevier
A new drug delivery system (DDS) type complexing magnetic nanoparticles (MNP) along
with boron nanosheets (BNN) coated with a pH-responsive polymer-polyethylene glycol …

A multi-stimuli responsive alginate nanogel for anticancer chemo-photodynamic therapy

S Pillarisetti, V Vijayan, J Rangasamy… - Journal of Industrial and …, 2023 - Elsevier
Stimuli-responsive nanosystems enable highly effective targeting and therapeutic functions,
including chemotherapy and photodynamic therapy (PDT). Traditional PDT alone cannot …

Recent advances in stimuli-responsive doxorubicin delivery systems for liver cancer therapy

ER Radu, A Semenescu, SI Voicu - Polymers, 2022 - mdpi.com
Doxorubicin (DOX) is one of the most commonly used drugs in liver cancer. Unfortunately,
the traditional chemotherapy with DOX presents many limitations, such as a systematic …

Current principles, challenges, and new metrics in pH-responsive drug delivery systems for systemic cancer therapy

RA Verkhovskii, AN Ivanov, EV Lengert, KA Tulyakova… - Pharmaceutics, 2023 - mdpi.com
The paradigm of drug delivery via particulate formulations is one of the leading ideas that
enable overcoming limitations of traditional chemotherapeutic agents. The trend toward …

Dual stimuli-responsive polymeric microgels for enhanced doxorubicin delivery to hepatocellular carcinoma

SC Kunene, KS Lin, MT Weng, MJC Espinoza… - Journal of Drug Delivery …, 2023 - Elsevier
Liver cancer remains a big challenge to treat owing to its recurrence and high rates of
metastasis; hence, the treatments for this type of cancer remains unachieved. Recently …

Synthesis of cationic gel-coated hydroxyapatite composites for pH-and thermo-responsive drug delivery in tumor microenvironments

NV Mdlovu, RS Juang, MT Weng, KS Lin… - Journal of Drug Delivery …, 2024 - Elsevier
Nanomedicine has gained a significant attention in biomedical science and engineering. It
involves design and applications of engineered composites for targeted delivery …

In vivo and in vitro studies of magnetic silica nanocomposites decorated with Pluronic F127 for controlled drug delivery system

MJC Espinoza, KS Lin, MT Weng, SC Kunene… - Journal of Industrial and …, 2022 - Elsevier
The current study presents the synthesis and characterization of magnetic silica
nanocomposites (MSNCs) decorated with Pluronic F127. The nanocomposites were loaded …