Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties

X Zhang, L Xie, J Long, Q Xie, Y Zheng, K Liu… - Chemico-Biological …, 2021 - Elsevier
Salidroside has been identified as one of the most potent compounds isolated from various
Rhodiola plants, which have been used for a long time as adaptogens in traditional Chinese …

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease

EJ Seo, N Fischer, T Efferth - Pharmacological research, 2018 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia. The exact pathophysiology
of this disease remains incompletely understood and safe and effective therapies are …

Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs

R Hu, M Wang, S Ni, M Wang, L Liu, H You… - European Journal of …, 2020 - Elsevier
Endothelial dysfunction plays important roles in vascular dysfunction under diabetic
conditions. The generation of advanced glycation end products (AGEs), which can induce …

[HTML][HTML] Phytochemicals targeting NF-κB signaling: Potential anti-cancer interventions

A Chauhan, AU Islam, H Prakash, S Singh - Journal of pharmaceutical …, 2022 - Elsevier
Nuclear factor κB (NF-κB) is a ubiquitous regulator of the signalome and is indispensable for
various biological cell functions. NF-κB consists of five transcription factors that execute both …

[HTML][HTML] Salidroside as a potential neuroprotective agent for ischemic stroke: a review of sources, pharmacokinetics, mechanism and safety

F Fan, L Yang, R Li, X Zou, N Li, X Meng… - Biomedicine & …, 2020 - Elsevier
Salidroside (Sal) is a bioactive extract principally from traditional herbal medicine such as
Rhodiola rosea L., which has been commonly used for hundreds of years in Asia countries …

Salidroside ameliorates cognitive impairment in a d-galactose-induced rat model of Alzheimer's disease

J Gao, H He, W Jiang, X Chang, L Zhu, F Luo… - Behavioural brain …, 2015 - Elsevier
The purpose of the present study was to investigate possible preventive effects of
salidroside (sal) on a rat model of Alzheimer's disease and to explore its possible …

The cardioprotective effect of salidroside against myocardial ischemia reperfusion injury in rats by inhibiting apoptosis and inflammation

L Zhu, T Wei, J Gao, X Chang, H He, F Luo, R Zhou… - Apoptosis, 2015 - Springer
The main purpose of this study was to investigate effect of salidroside (Sal) on myocardial
ischemia reperfusion injury in rats and the underlying mechanism. Myocardial ischemia …

Anticancer effect of salidroside on A549 lung cancer cells through inhibition of oxidative stress and phospho-p38 expression

J Wang, JZ Li, AX Lu, KF Zhang… - Oncology letters, 2014 - spandidos-publications.com
Oxidative stress is important in carcinogenesis and metastasis. Salidroside, a
phenylpropanoid glycoside isolated from Rhodiola rosea L., shows potent antioxidant …

[HTML][HTML] Rosenroot (Rhodiola): potential applications in aging-related diseases

W Zhuang, L Yue, X Dang, F Chen, Y Gong… - Aging and …, 2019 - ncbi.nlm.nih.gov
Aging is a progressive accumulation of changes in the body, which increases the
susceptibility to diseases such as Alzheimer's disease, Parkinson's disease …

Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats

AS Akinrinde, OE Adebiyi - Neurotoxicology, 2019 - Elsevier
Cobalt (Co) intoxication arising from occupational exposures and ion release from metal
implants has been associated with neurological alterations such as cognitive decline …