Phosphorylation at the homotypic interface regulates nucleoprotein oligomerization and assembly of the influenza virus replication machinery
Negative-sense RNA viruses assemble large ribonucleoprotein (RNP) complexes that direct
replication and transcription of the viral genome. Influenza virus RNPs contain the …
replication and transcription of the viral genome. Influenza virus RNPs contain the …
Host–rabies virus protein–protein interactions as druggable antiviral targets
UF Lingappa, X Wu, A Macieik, SF Yu… - Proceedings of the …, 2013 - National Acad Sciences
We present an unconventional approach to antiviral drug discovery, which is used to identify
potent small molecules against rabies virus. First, we conceptualized viral capsid assembly …
potent small molecules against rabies virus. First, we conceptualized viral capsid assembly …
Analysis of the dark proteome of Chandipura virus reveals maximum propensity for intrinsic disorder in phosphoprotein
Chandipura virus (CHPV, a member of the Rhabdoviridae family) is an emerging pathogen
that causes rapidly progressing influenza-like illness and acute encephalitis often leading to …
that causes rapidly progressing influenza-like illness and acute encephalitis often leading to …
hnRNPA1 impedes snakehead vesiculovirus replication via competitively disrupting viral phosphoprotein-nucleoprotein interaction and degrading viral …
AQ Liu, X Qin, H Wu, H Feng, YA Zhang, J Tu - Virulence, 2023 - Taylor & Francis
Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) plays an important role in
regulating the replication of many viruses. However, it remains elusive whether and how …
regulating the replication of many viruses. However, it remains elusive whether and how …
Microglial activation induces neuronal death in Chandipura virus infection
Neurotropic viruses induce neurodegeneration either directly by activating host death
domains or indirectly through host immune response pathways. Chandipura Virus (CHPV) …
domains or indirectly through host immune response pathways. Chandipura Virus (CHPV) …
Chandipura virus induces neuronal death through Fas-mediated extrinsic apoptotic pathway
Chandipura virus (CHPV; genus Vesiculovirus, family Rhabdoviridae) is an emerging
tropical pathogen with a case fatality rate of 55 to 75% that predominantly affects children in …
tropical pathogen with a case fatality rate of 55 to 75% that predominantly affects children in …
Ensemble structure of the highly flexible complex formed between vesicular stomatitis virus unassembled nucleoprotein and its phosphoprotein chaperone
F Yabukarski, C Leyrat, N Martinez… - Journal of Molecular …, 2016 - Elsevier
Nucleocapsid assembly is an essential process in the replication of the non-segmented,
negative-sense RNA viruses (NNVs). Unassembled nucleoprotein (N 0) is maintained in an …
negative-sense RNA viruses (NNVs). Unassembled nucleoprotein (N 0) is maintained in an …
Newly identified phosphorylation site in the vesicular stomatitis virus P protein is required for viral RNA synthesis
A Mondal, KG Victor, RS Pudupakam… - Journal of …, 2014 - Am Soc Microbiol
The vesicular stomatitis virus (VSV) RNA-dependent RNA polymerase consists of two viral
proteins; the large (L) protein is the main catalytic subunit, and the phosphoprotein (P) is an …
proteins; the large (L) protein is the main catalytic subunit, and the phosphoprotein (P) is an …
Development of a walleye spleen stromal cell line sensitive to viral hemorrhagic septicemia virus (VHSV IVb) and to protection by synthetic dsRNA
NTK Vo, AW Bender, DA Ammendolia… - Fish & Shellfish …, 2015 - Elsevier
A cell line, WE-spleen6, has been developed from the stromal layer of primary spleen cell
cultures. On conventional plastic, WE-spleen6 cells had a spindle-shaped morphology at …
cultures. On conventional plastic, WE-spleen6 cells had a spindle-shaped morphology at …
Intraviral protein interactions of Chandipura virus
Chandipura virus (CHPV) is an emerging rhabdovirus responsible for several outbreaks of
fatal encephalitis among children in India. The characteristic structure of the virus is a result …
fatal encephalitis among children in India. The characteristic structure of the virus is a result …