Fighting antibiotic resistance in hospital-acquired infections: current state and emerging technologies in disease prevention, diagnostics and therapy
E Avershina, V Shapovalova, G Shipulin - Frontiers in microbiology, 2021 - frontiersin.org
Rising antibiotic resistance is a global threat that is projected to cause more deaths than all
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …
Clinical Diagnostics of Bacterial Infections and Their Resistance to Antibiotics—Current State and Whole Genome Sequencing Implementation Perspectives
Antimicrobial resistance (AMR), defined as the ability of microorganisms to withstand
antimicrobial treatment, is responsible for millions of deaths annually. The rapid spread of …
antimicrobial treatment, is responsible for millions of deaths annually. The rapid spread of …
Hybrid Assembly Provides Improved Resolution of Plasmids, Antimicrobial Resistance Genes, and Virulence Factors in Escherichia coli and Klebsiella pneumoniae …
Emerging new sequencing technologies have provided researchers with a unique
opportunity to study factors related to microbial pathogenicity, such as antimicrobial …
opportunity to study factors related to microbial pathogenicity, such as antimicrobial …
A Practical Approach for Predicting Antimicrobial Phenotype Resistance in Staphylococcus aureus Through Machine Learning Analysis of Genome Data
With the reduction in sequencing price and acceleration of sequencing speed, it is
particularly important to directly link the genotype and phenotype of bacteria. Here, we firstly …
particularly important to directly link the genotype and phenotype of bacteria. Here, we firstly …
[HTML][HTML] Meat safety legislation and its opportunities and hurdles for innovative approaches: A review
GE Nagel-Alne, E Murphy, B McCauslin, SJ Hauge… - Food Control, 2022 - Elsevier
Albert Einstein has been quoted “We cannot solve our problems with the same thinking we
used when we created them”. Innovations are necessary to meet future challenges …
used when we created them”. Innovations are necessary to meet future challenges …
A 6-Year Update on the Diversity of Methicillin-Resistant Staphylococcus aureus Clones in Africa: A Systematic Review
Background Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of
hospital-associated (HA) and community-associated (CA) infections globally. The multi-drug …
hospital-associated (HA) and community-associated (CA) infections globally. The multi-drug …
Highly sensitive quantitative phase microscopy and deep learning aided with whole genome sequencing for rapid detection of infection and antimicrobial resistance
Current state-of-the-art infection and antimicrobial resistance (AMR) diagnostics are based
on culture-based methods with a detection time of 48–96 h. Therefore, it is essential to …
on culture-based methods with a detection time of 48–96 h. Therefore, it is essential to …
Genomic features associated with the degree of phenotypic resistance to carbapenems in carbapenem-resistant Klebsiella pneumoniae
Carbapenem-resistant Klebsiella pneumoniae strains cause severe infections that are
difficult to treat. The production of carbapenemases such as the K. pneumoniae …
difficult to treat. The production of carbapenemases such as the K. pneumoniae …
Ultrafast and cost-effective pathogen identification and resistance gene detection in a clinical setting using nanopore flongle sequencing
E Avershina, SA Frye, J Ali, AM Taxt… - Frontiers in …, 2022 - frontiersin.org
Rapid bacterial identification and antimicrobial resistance gene (ARG) detection are crucial
for fast optimization of antibiotic treatment, especially for septic patients where each hour of …
for fast optimization of antibiotic treatment, especially for septic patients where each hour of …
A culture-, amplification-independent, and rapid method for identification of pathogens and antibiotic resistance profile in bovine mastitis milk
Introduction Rapid and accurate diagnosis of causative pathogens in mastitis would
minimize the imprudent use of antibiotics and, therefore, reduce the spread of antimicrobial …
minimize the imprudent use of antibiotics and, therefore, reduce the spread of antimicrobial …