Role of YAP1 signaling in biliary development, repair, and disease

L Molina, K Nejak-Bowen… - Seminars in liver …, 2022 - thieme-connect.com
Yes-associated protein 1 (YAP1) is a transcriptional coactivator that activates transcriptional
enhanced associate domain transcription factors upon inactivation of the Hippo signaling …

Cellular plasticity at the nexus of development and disease

LB Spatz, RU Jin, JC Mills - Development, 2021 - journals.biologists.com
ABSTRACT In October 2020, the Keystone Symposia Global Health Series hosted a
Keystone eSymposia entitled 'Tissue Plasticity: Preservation and Alteration of Cellular …

Reversine attenuates cholestatic ductular reaction in rats

D Huang, L Tang, T Li, P Li, Z Huang, J Weng… - FEBS Open …, 2023 - Wiley Online Library
Ductular reaction (DR) is usually observed in biliary disorders or various liver disorders,
including nonalcoholic fatty liver disease. Few studies have focused on interrupting the DR …

Relationships between congenital peritoneopericardial diaphragmatic hernia or congenital central diaphragmatic hernia and ductal plate malformations in dogs and …

LM Seibert, SA Center, JF Randolph… - Journal of the …, 2021 - Am Vet Med Assoc
OBJECTIVE To characterize the association between peritoneopericardial diaphragmatic
hernia (PPDH) or congenital central diaphragmatic hernia (CCDH) and ductal plate …

Yap signalling regulates ductular reactions in mice with CRISPR/Cas9-induced glycogen storage disease type Ia

Y Xie, B Hu, Y Gao, Y Tang, G Chen… - Animal Cells and …, 2022 - Taylor & Francis
Glycogen storage disease type Ia (GSD-Ia) is caused by a deficiency in the glucose-6-
phosphatase (G6Pase, G6pc) enzyme, which catalyses the final step of gluconeogenesis …

牛磺胆酸促进肝硬化发展的机制.

乐英彪, 王昆华, 邹雷 - Journal of Clinical Hepatology …, 2021 - search.ebscohost.com
胆汁酸是胆汁的主要成分, 其外分泌入肠道帮助脂质和脂溶性维生素的吸收,
也可作为信号分子调节胆汁酸代谢, 帮助维持肠道稳态. 而肝硬化过程中伴有不同程度的胆汁 …

YAP1 Signaling in Hepatobiliary Development and Oncogenesis

LM Molina - 2021 - search.proquest.com
Abstract Yes-associated protein 1 (YAP1) is critical for liver development, regeneration, and
oncogenesis. In this thesis, I studied the physiological role of YAP1 in early liver …

Mechanism of taurocholic acid in promoting the progression of liver cirrhosis

YUE Yingbiao, ZOU Lei - 临床肝胆病杂志, 2021 - lcgdbzz.org
Bile acid is the main component of bile, and the external secretion of bile acid into the
intestine can help with the absorption of lipids and fat-soluble vitamins; in addition, bile acid …