The overconsumption of highly caloric and palatable foods has caused a surge in obesity
rates in the past half century, thereby posing a healthcare challenge due to the array of …

The hypothalamus (“hypo” meaning below, and “thalamus” meaning bed) consists of
regulatory circuits that support basic life functions that ensure survival. Sitting at the interface …

The hypothalamus plays a key role in coordinating fundamental body functions. Despite
recent progress in single-cell technologies, a unified catalog and molecular characterization …

Antisense oligonucleotides (ASOs) dosed into cerebrospinal fluid (CSF) distribute broadly
throughout the central nervous system (CNS). By modulating RNA, they hold the promise of …

Short-term memory deficits have been associated with prefrontal cortex (PFC) dysfunction in
Alzheimer's disease (AD) and AD mouse models. Extratelencephalic projection (ET) …

The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …

Motivated behaviors are often studied in isolation to assess labeled lines of neural
connections underlying innate actions. However, in nature, multiple systems compete for …

The lateral septum (LS) has been implicated in the regulation of locomotion. Nevertheless,
the neurons synchronizing LS activity with the brain's clock in the suprachiasmatic nucleus …

The hypothalamus is an evolutionarily conserved endocrine interface that, among other
roles, links central homeostatic control to adaptive bodily responses by releasing hormones …

The hypothalamus is a brain region that integrates signals from the periphery and the
environment to maintain organismal homeostasis. To do so, specialized hypothalamic …