Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Neuromodulatory effects and targets of the SCFAs and gasotransmitters produced by the human symbiotic microbiota

AV Oleskin, BA Shenderov - Microbial ecology in health and …, 2016 - Taylor & Francis
The symbiotic gut microbiota plays an important role in the development and homeostasis of
the host organism. Its physiological, biochemical, behavioral, and communicative effects are …

The Triple Crown: NO, CO, and H2S in cancer cell biology

PP Oza, K Kashfi - Pharmacology & Therapeutics, 2023 - Elsevier
Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) are three
endogenously produced gases with important functions in the vasculature, immune defense …

Hydrogen sulfide: a novel player in airway development, pathophysiology of respiratory diseases, and antiviral defenses

N Bazhanov, M Ansar, T Ivanciuc… - American journal of …, 2017 - atsjournals.org
Hydrogen sulfide (H2S) is a biologically relevant signaling molecule in mammals. Along with
the volatile substances nitric oxide (NO) and carbon monoxide (CO), H2S is defined as a …

Biological effects of thermal water-associated hydrogen sulfide on human airways and associated immune cells: implications for respiratory diseases

J Viegas, AF Esteves, EM Cardoso, FA Arosa… - Frontiers in Public …, 2019 - frontiersin.org
Natural mineral (thermal) waters have been used for centuries as treatment for various
diseases. However, the scientific background of such therapeutic action is mostly empiric …

A case for hydrogen sulfide metabolism as an oxygen sensing mechanism

KR Olson - Antioxidants, 2021 - mdpi.com
The ability to detect oxygen availability is a ubiquitous attribute of aerobic organisms.
However, the mechanism (s) that transduce oxygen concentration or availability into …

The epithelial sodium channel δ-subunit: new notes for an old song

T Giraldez, P Rojas, J Jou, C Flores… - American Journal …, 2012 - journals.physiology.org
Amiloride-sensitive epithelial Na+ channels (ENaCs) can be formed by different
combinations of four homologous subunits, named α, β, γ, and δ. In addition to providing an …

Gasping for sulfide: a critical appraisal of hydrogen sulfide in lung disease and accelerated aging

D Pacitti, CJ Scotton, V Kumar, H Khan… - Antioxidants & Redox …, 2021 - liebertpub.com
Hydrogen sulfide (H2S) is a gaseous signaling molecule involved in a plethora of
physiological and pathological processes. It is primarily synthesized by cystathionine-β …

Hydrogen sulphide‐induced relaxation of porcine peripheral bronchioles

S Rashid, JK Heer, MJ Garle… - British journal of …, 2013 - Wiley Online Library
Background and Purpose Hydrogen sulphide (H2S) is an endogenous gasotransmitter.
Although it has been shown to elicit responses in vascular and other smooth muscle …

Epithelial electrolyte transport physiology and the gasotransmitter hydrogen sulfide

E Pouokam, M Althaus - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Hydrogen sulfide (H2S) is a well‐known environmental chemical threat with an unpleasant
smell of rotten eggs. Aside from the established toxic effects of high‐dose H2S, research …