The rising threats to worldwide security (affecting the military, first responders, and civilians)
urge us to develop efficient and versatile technological solutions to protect human beings …

The hemorrhagic fever viruses (HFVs) cause severe or fatal infections in humans. Named
after their common symptom hemorrhage, these viruses induce significant vascular …

Background Lassa fever is a viral haemorrhagic fever endemic to eight West African
countries. Symptomatic disease is expected to occur in 20% of those infected and …

Background: Lassa virus (LASV) can cause severe acute systemic infection in humans. No
approved antiviral drugs or vaccines are currently available. Antibody-based therapeutics …

Lassa virus (LASV), an Old World arenavirus, is responsible for hemorrhagic fevers in
western Africa. The privileged tropism of LASV for endothelial cells combined with a …

Summary Background Managing Lassa fever (LF) patients is challenging because of the
complexity of this life-threatening infectious disease, the necessary isolation measures, and …

Viral hemorrhagic fevers (HF) are a group of acute febrile diseases with high mortality rates.
Although hemostatic dysfunction appears to be a major determinant of the severity of the …

Viruses infect millions of people each year. Both endemic viruses circulating throughout the
population as well as novel epidemic and pandemic viruses pose ongoing threats to global …

Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum
antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this …

Background: Lassa fever (LF) infection is one of the viral hemorrhagic fever diseases found
mainly in Sub-Saharan West Africa, including Nigeria. The case fatality rate is 60% among …