Super shedding in enteric pathogens: a review

F Kempf, R La Ragione, B Chirullo, C Schouler… - Microorganisms, 2022 - mdpi.com
Super shedding occurs when a small number of individuals from a given host population
shed high levels of a pathogen. Beyond this general definition, various interpretations of the …

Precision public health to inhibit the contagion of disease and move toward a future in which microbes spread health

DS Thaler, MG Head, A Horsley - BMC infectious diseases, 2019 - Springer
Antimicrobial resistance continues to outpace the development of new chemotherapeutics.
Novel pathogens continue to evolve and emerge. Public health innovation has the potential …

Alteration of a Shiga toxin-encoding phage associated with a change in toxin production level and disease severity in Escherichia coli

T Miyata, I Taniguchi, K Nakamura… - Microbial …, 2023 - microbiologyresearch.org
Among the nine clades of Shiga toxin (Stx)-producing Escherichia coli O157: H7, clade 8 is
thought to be highly pathogenic, as it causes severe disease more often than other clades …

Strain and host-cell dependent role of type-1 fimbriae in the adherence phenotype of super-shed Escherichia coli O157: H7

R Katani, IT Kudva, S Srinivasan, JB Stasko… - International Journal of …, 2021 - Elsevier
Super-shed (SS) Escherichia coli O157 (E. coli O157) demonstrate a strong, aggregative,
locus of enterocyte effacement (LEE)-independent adherence phenotype on bovine recto …

Genetic and Functional Analyses of Virulence Potential of an Escherichia coli O157:H7 Strain Isolated From Super-Shedder Cattle

L Teng, S Lee, D Park, KC Jeong - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Shiga toxin (Stx)-producing Escherichia coli (STEC) O157: H7 is an enteric pathogen that
causes life-threatening disease in humans, with cattle being major natural reservoirs. A …

Comparative genomics analysis and characterization of Shiga toxin-producing Escherichia coli O157:H7 strains reveal virulence genes, resistance genes, prophages …

N Naidoo, OT Zishiri - BMC genomics, 2023 - Springer
Escherichia coli O157: H7 is a foodborne pathogen that has been linked to global disease
outbreaks. These diseases include hemorrhagic colitis and hemolytic uremic syndrome. It is …

In Silico Analysis of Shiga Toxin-Producing Escherichia coli O157:H7 Strains from Presumptive Super- and Low-Shedder Cattle

EW Bumunang, VS Castro, T Alexander, R Zaheer… - Toxins, 2024 - mdpi.com
Cattle are the primary reservoir for STEC O157, with some shedding> 104 CFU/g in feces, a
phenomenon known as super-shedding (SS). The mechanism (s) responsible for SS are not …

Construction of a Lectin–Glycan Interaction Network from Enterohemorrhagic Escherichia coli Strains by Multi-omics Analysis

SH Cho, KM Lee, CH Kim, SS Kim - International Journal of Molecular …, 2020 - mdpi.com
Enterohemorrhagic Escherichia coli (EHEC) causes hemorrhagic colitis and hemolytic
uremic syndrome. EHEC infection begins with bacterial adherence to the host intestine via …

Investigating the adherence factors of Escherichia coli at the bovine recto-anal junction

EM Nawrocki, IT Kudva, EG Dudley - Microbiology Spectrum, 2024 - journals.asm.org
Shiga toxin–producing Escherichia coli (STEC) are major foodborne pathogens that result in
thousands of hospitalizations each year in the United States. Cattle, the natural reservoir …

[HTML][HTML] Farm animal contact is associated with progression to Hemolytic uremic syndrome in patients with Shiga toxin-producing Escherichia coli—Indiana, 2012 …

MS Vachon, M Khalid, GAM Tarr, C Hedberg, JA Brown - One Health, 2020 - Elsevier
Background Hemolytic uremic syndrome (HUS) is a life-threatening complication of Shiga
toxin-producing Escherichia coli (STEC) infection. The relationship between STEC exposure …