Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

High-density lipoproteins (HDLs) represent a family of particle characterized by the
presence of apolipoprotein AI (apoA-I) and by their ability to transport cholesterol from …

There are several well-documented functions of high-density lipoprotein (HDL) that may
explain the ability of these lipoproteins to protect against atherosclerosis. The best …

Since the first discovery of an inverse correlation between high‐density lipoprotein‐
cholesterol (HDL‐C) levels and coronary heart disease in the 1950s the life cycle of HDL, its …

High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with
many minor proteins and lipids that influence the function of HDL. Although HDL is a …

Tissue factor (TF), formerly known as thromboplastin, is the key initiator of the coagulation
cascade; it binds factor VIIa resulting in activation of factor IX and factor X, ultimately leading …

In addition to its role in reverse cholesterol transport, high-density lipoprotein (HDL)
cholesterol has direct action on numerous cell types that influence cardiovascular and …

Aims High-density lipoprotein cholesterol (HDL-C) is inversely associated with
cardiovascular (CV) events and thus an attractive therapeutic target. However, in spite of …

High‐density lipoproteins (HDLs) represent a family of particles characterized by the
presence of apolipoprotein A‐I (apo A‐I) and by their ability to transport cholesterol from …

2433 Multifunctional but Vulnerable HDL munication of results. 15 As yet, clinical and
epidemiological studies have come to discrepant and inconsistent conclusions on the …