Advances in understanding the physiologic functions of the tumor necrosis factor
superfamily (TNFSF) of ligands, receptors, and signaling networks are providing deeper …

Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs …

In recent years there has been tremendous progress towards deep molecular
characterization of cell types using single cell transcriptome sequencing. Here we report a …

The increasing generation of population-level single-cell atlases has the potential to link
sample metadata with cellular data. Constructing such references requires integration of …

Longitudinal bulk and single-cell omics data is increasingly generated for biological and
clinical research but is challenging to analyze due to its many intrinsic types of variations …

Background Ex vivo assays of platelet function critically inform mechanistic and clinical
hematology studies, where effects of divergent blood processing methods on platelet …

Renal transplantation is currently the treatment of choice for end-stage kidney disease,
enabling a quality of life superior to dialysis. Despite this, all transplanted patients are at risk …

Preserving the in vivo cell transcriptome is essential for accurate profiling, yet factors during
cell isolation including time ex vivo and temperature induce artifactual gene expression …

Proteomics tools provide a powerful means to identify, detect, and quantify protein-related
details in studies of platelet phenotype and function. Here, we consider how historical and …

Immunophenotyping using high dimensional flow cytometry is a central component of
human immune system multi‐omic studies. We present four high parameter flow cytometry …