Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association
The year 2014 marked the 20th anniversary of the coining of the term proteomics. The
purpose of this scientific statement is to summarize advances over this period that have …
purpose of this scientific statement is to summarize advances over this period that have …
Connections for matters of the heart: network medicine in cardiovascular diseases
AR Sonawane, E Aikawa, M Aikawa - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) are diverse disorders affecting the heart and vasculature in
millions of people worldwide. Like other fields, CVD research has benefitted from the deluge …
millions of people worldwide. Like other fields, CVD research has benefitted from the deluge …
Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association
This update expands the prior scientific statement on the relevance of genetics and
genomics for the prevention and treatment of CVDs. 2 In the earlier report, we focused on …
genomics for the prevention and treatment of CVDs. 2 In the earlier report, we focused on …
Decoded cardiopoietic cell secretome linkage to heart repair biosignature
Cardiopoiesis-primed human stem cells exert sustained benefit in treating heart failure
despite limited retention following myocardial delivery. To assess potential paracrine …
despite limited retention following myocardial delivery. To assess potential paracrine …
Network biology in medicine and beyond
Figure 1. A, An example of MEF2A transcriptional network derived from Encyclopedia of
DNA Elements data. 15 B, Kyoto Encyclopedia of Genes and Genomes (KEGG) cell cycle …
DNA Elements data. 15 B, Kyoto Encyclopedia of Genes and Genomes (KEGG) cell cycle …
Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association
The field of genetics and genomics has advanced considerably with the achievement of
recent milestones encompassing the identification of many loci for cardiovascular disease …
recent milestones encompassing the identification of many loci for cardiovascular disease …
Proteomic identification of matrix metalloproteinase substrates in the human vasculature
C Stegemann, A Didangelos… - Circulation …, 2013 - Am Heart Assoc
Background—Matrix metalloproteinases (MMPs) play a key role in cardiovascular disease,
in particular aneurysm formation and plaque rupture. Surprisingly, little is known about MMP …
in particular aneurysm formation and plaque rupture. Surprisingly, little is known about MMP …
Cardiopoietic stem cell therapy restores infarction-altered cardiac proteome
Cardiopoietic stem cells have reached advanced clinical testing for ischemic heart failure.
To profile their molecular influence on recipient hearts, systems proteomics was here …
To profile their molecular influence on recipient hearts, systems proteomics was here …
Metabolome and metaboproteome remodeling in nuclear reprogramming
CDL Folmes, DK Arrell, J Zlatkovic-Lindor… - Cell Cycle, 2013 - Taylor & Francis
Nuclear reprogramming resets differentiated tissue to generate induced pluripotent stem
(iPS) cells. While genomic attributes underlying reacquisition of the embryonic-like state …
(iPS) cells. While genomic attributes underlying reacquisition of the embryonic-like state …
An overview of the human brain myelin proteome and differences associated with schizophrenia
D Martins-de-Souza, PC Guest… - The World Journal of …, 2021 - Taylor & Francis
Objectives Disturbances in the myelin sheath drive disruptions in neural transmission and
brain connectivity as seen in schizophrenia. Here, the myelin proteome was characterised in …
brain connectivity as seen in schizophrenia. Here, the myelin proteome was characterised in …