Assessment of cerebral autoregulatory function and inter-hemispheric blood flow in older adults with internal carotid artery stenosis using transcranial Doppler …

R Magyar-Stang, H Pál, B Csányi, A Gaál, Z Mihály… - GeroScience, 2023 - Springer
Unhealthy vascular aging promotes atherogenesis, which may lead to significant internal
carotid artery stenosis (CAS) in 5 to 7.5% of older adults. The pathogenic factors that …

A 3D‐1D coupled blood flow and oxygen transport model to generate microvascular networks

T Köppl, E Vidotto, B Wohlmuth - International journal for …, 2020 - Wiley Online Library
In this work, we introduce an algorithmic approach to generate microvascular networks
starting from larger vessels that can be reconstructed without noticeable segmentation …

[图书][B] Cerebral blood flow and metabolism: a quantitative approach

SJ Payne - 2018 - World Scientific
The human brain is possibly the most complex organ in existence. This complexity means
that it is capable of great feats, yet has ensured that it remains surprisingly poorly …

A coupled lumped-parameter and distributed network model for cerebral pulse-wave hemodynamics

J Ryu, X Hu, SC Shadden - Journal of …, 2015 - asmedigitalcollection.asme.org
The cerebral circulation is unique in its ability to maintain blood flow to the brain under
widely varying physiologic conditions. Incorporating this autoregulatory response is …

Understanding perioperative risk determinants in carotid endarterectomy: the impact of compromised circle of Willis morphology on inter-hemispheric blood flow …

Z Czinege, ÁD Sándor, D Gyürki, A Varga, T Csípő… - GeroScience, 2024 - Springer
Carotid artery stenosis (CAS) often requires surgical intervention through carotid
endarterectomy (CEA) to prevent stroke. Accurate cerebrovascular risk assessments are …

Numerical modelling of a peripheral arterial stenosis using dimensionally reduced models and kernel methods

T Koeppl, G Santin, B Haasdonk… - International journal for …, 2018 - Wiley Online Library
In this work, we consider 2 kinds of model reduction techniques to simulate blood flow
through the largest systemic arteries, where a stenosis is located in a peripheral artery, ie, in …

On the anatomical definition of arterial networks in blood flow simulations: comparison of detailed and simplified models

PJ Blanco, LO Müller, SM Watanabe… - … and Modeling in …, 2020 - Springer
The goal of this work is to assess the impact of vascular anatomy definition degree in the
predictions of blood flow models of the arterial network. To this end, results obtained with an …

NO Deficiency Compromises Inter-and Intrahemispheric Blood Flow Adaptation to Unilateral Carotid Artery Occlusion

L Hricisák, É Pál, D Nagy, M Delank… - International Journal of …, 2024 - mdpi.com
Carotid artery stenosis (CAS) affects approximately 5–7.5% of older adults and is
recognized as a significant risk factor for vascular cognitive impairment (VCI). The impact of …

Numerical modeling of compensation mechanisms for peripheral arterial stenoses

D Drzisga, T Köppl, U Pohl, R Helmig… - Computers in biology and …, 2016 - Elsevier
The goal of this paper is to develop a numerical model for physiological mechanisms that
help to compensate reduced blood flow caused by a peripheral arterial stenosis. Thereby …

Multi-scale modeling of flow and transport processes in arterial networks and tissue

TT Köppl - 2015 - mediatum.ub.tum.de
This thesis is concerned with the simulation of blood flow and mass transport in vascularized
human tissue. Our mathematical model is based on a domain decomposition approach, ie …