Although it has been widely applied in identification of genes responsible for biomedically,
economically, or even evolutionarily important complex and quantitative traits, traditional …

Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative …

Major depressive disorder (MDD) is a common complex trait with enormous public health
significance. As part of the Genetic Association Information Network initiative of the US …

Objective: The authors used a custom array of 1,536 single-nucleotide polymorphisms
(SNPs) to interrogate 94 functionally relevant candidate genes for schizophrenia and identify …

Little is known for certain about the genetics of schizophrenia. The advent of genomewide
association has been widely anticipated as a promising means to identify reproducible DNA …

BACKGROUND: Genetic association studies are widely used in biomedical research and
yet only a minority of positive findings stand the test of replication. I explored the capacity of …

Pharmacogenetics holds promise in HIV treatment because of the complexity and potential
toxicity of multidrug therapies that are prescribed for long periods. Thus far, few candidate …

A region along chromosome 7q was recently linked to components of the metabolic
syndrome (MetS) in several genome-wide linkage studies. Within this region, the CD36 …

Schizophrenia is an often devastating neuropsychiatric illness. Understanding the genetic
variation affecting response to antipsychotics is important to develop novel diagnostic tests …

While it is clear that schizophrenia is highly heritable, the genetic basis of this heritability is
complex. Human genetic, brain imaging, and model organism studies have met with only …