Membrane electroporation and electropermeabilization: mechanisms and models

T Kotnik, L Rems, M Tarek… - Annual review of …, 2019 - annualreviews.org
Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient
increase in their plasma membrane permeability, allowing transmembrane transport of …

Electroporation in food processing and biorefinery

S Mahnič-Kalamiza, E Vorobiev, D Miklavčič - The Journal of membrane …, 2014 - Springer
Electroporation is a method of treatment of plant tissue that due to its nonthermal nature
enables preservation of the natural quality, colour and vitamin composition of food products …

Design and optimization of a light-emitting diode projection micro-stereolithography three-dimensional manufacturing system

X Zheng, J Deotte, MP Alonso, GR Farquar… - Review of Scientific …, 2012 - pubs.aip.org
The rapid manufacture of complex three-dimensional micro-scale components has eluded
researchers for decades. Several additive manufacturing options have been limited by either …

The effects of electroporation buffer composition on cell viability and electro-transfection efficiency

JJ Sherba, S Hogquist, H Lin, JW Shan, DI Shreiber… - Scientific reports, 2020 - nature.com
Electroporation is an electro-physical, non-viral approach to perform DNA, RNA, and protein
transfections of cells. Upon application of an electric field, the cell membrane is …

Multimicrochannel microneedle microporation platform for enhanced intracellular drug delivery

L Lin, Y Wang, M Cai, X Jiang, Y Hu… - Advanced Functional …, 2022 - Wiley Online Library
Common delivery routes for chemotherapeutics are based on circulation, which faces
clinical limitations to local delivery efficiency, and the conflict between the dose for …

Tutorial: Electroporation of cells in complex materials and tissue

L Rems, D Miklavčič - Journal of Applied Physics, 2016 - pubs.aip.org
Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …

[HTML][HTML] Models of electroporation and the associated transmembrane molecular transport should be revisited

M Scuderi, J Dermol-Černe, CA da Silva… - …, 2022 - Elsevier
Electroporation has become a powerful tool for nonviral delivery of various biomolecules
such as nucleic acids, proteins, and chemotherapeutic drugs to virtually any living cell by …

[HTML][HTML] Revisiting the role of pulsed electric fields in overcoming the barriers to in vivo gene electrotransfer

S Sachdev, T Potočnik, L Rems, D Miklavčič - Bioelectrochemistry, 2022 - Elsevier
Gene therapies are revolutionizing medicine by providing a way to cure hitherto incurable
diseases. The scientific and technological advances have enabled the first gene therapies to …

Cell membrane transport mechanisms: ion channels and electrical properties of cell membranes

J Kulbacka, A Choromańska, J Rossowska… - Transport across natural …, 2017 - Springer
Cellular life strongly depends on the membrane ability to precisely control exchange of
solutes between the internal and external (environmental) compartments. This barrier …

Basic features of a cell electroporation model: illustrative behavior for two very different pulses

RS Son, KC Smith, TR Gowrishankar… - The Journal of …, 2014 - Springer
Science increasingly involves complex modeling. Here we describe a model for cell
electroporation in which membrane properties are dynamically modified by poration. Spatial …