Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

Introduction: Big-data-driven drug development resources and methodologies have been
evolving with ever-expanding data from large-scale biological experiments, clinical trials …

The malignant neoplasm of the cervix, cervical cancer, has effects on the reproductive tract.
Although infection with oncogenic human papillomavirus is essential for cervical cancer …

Alzheimer's disease (AD) is a dynamic degeneration of the brain with progressive dementia.
Considering the uncertainties in its molecular mechanism, in the present study, we …

Aim To explore whether plasma microRNA‐16‐5p,‐17‐5p and‐20a‐5p can be used as
diagnostic biomarkers in gestational diabetes mellitus (GDM) and to investigate the …

Tissue-specific mechanisms prompting obesity-related development complications in
humans remain unclear. We apply multiomics analyses of subcutaneous adipose tissue and …

Background and objectives: Colorectal cancer (CRC) is the second most common cause of
cancer-related death in the world, but early diagnosis ameliorates the survival of CRC. This …

Type 2 diabetes mellitus (T2DM) is one of the most common diseases of endocrine and
metabolic disorders, whose mechanism is still largely unknown. Fortunately, various “omics” …

Ovarian cancer is one of the most significant disease among gynecological disorders that
women suffered from over the centuries. However, disease-specific and effective biomarkers …

Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance,
with onset or first recognition during second or third trimester of gestation. It is estimated that …