Bone fractures and segmental bone defects are a significant source of patient morbidity and
place a staggering economic burden on the healthcare system. The annual cost of treating …

Scientific advancements in biomaterials, cellular therapies, and growth factors have brought
new therapeutic options for periodontal and peri‐implant reconstructive procedures. These …

Disclosure: The authors indicated that no external funding was received for any aspect of
this work. On the Disclosure of Potential Conflicts of Interest forms, which are provided with …

This systematic review aims to evaluate mesenchymal stem cells (MSC) periodontal
regenerative potential in animal models. MEDLINE, EMBASE and LILACS databases were …

Objective In patients with osteoarthritis (OA), bone marrow lesions (BMLs) are intimately
linked to disease progression. We hypothesized that aberrant multipotential stromal cell …

Aim The objective of the present review was to answer the focused question: what is the
effect of cell therapy in terms of orofacial bone regeneration compared to grafting with only …

A substantial proportion of fractures can present with nonunion, and the management of
nonunion continues to present a challenge for orthopaedic surgeons. A variety of biological …

Background Defective cellular elements constitute an important challenge to achieve
predictable periodontal regeneration. In an attempt to improve the cellularity of periodontal …

Objective The aim of this study was to retrospectively analyze the experience of treating long
segmental bone defects. Bone union was used as the criteria for the assessment of the …

Background: Connective tissue progenitors (CTPs) from native bone marrow (BM) or their
culture-expanded progeny, often referred to as mesenchymal stem/stromal cells, represents …