Drug delivery of gelatin nanoparticles as a biodegradable polymer for the treatment of infectious diseases: perspectives and challenges

OA Madkhali - Polymers, 2023 - mdpi.com
In recent years, there has been a growing interest in the use of gelatin nanoparticles (GNPs)
for the treatment of infectious diseases. The inherent properties of these nanoparticles make …

Ultrastructural Alterations of the Human Pathogen Giardia intestinalis after Drug Treatment

M Benchimol, AP Gadelha, W de Souza - Pathogens, 2023 - mdpi.com
This review presents the main cell characteristics altered after in vitro incubation of the
parasite with commercial drugs used to treat the disease caused by Giardia intestinalis. This …

Fused Enzyme Glucose-6-Phosphate Dehydrogenase:: 6-Phosphogluconolactonase (G6PD:: 6PGL) as a Potential Drug Target in Giardia lamblia, Trichomonas …

L Morales-Luna, M Vázquez-Bautista… - Microorganisms, 2024 - mdpi.com
Several microaerophilic parasites such as Giardia lamblia, Trichomonas vaginalis, and
Plasmodium falciparum are major disease-causing organisms and are responsible for …

Leishmania donovani 6-phosphogluconolactonase: Crucial for growth and host infection?

A Paul, PK Roy, NK Babu, TT Dhumal, S Singh - Microbial Pathogenesis, 2023 - Elsevier
The hexose monophosphate shunt is a crucial pathway in a variety of microorganisms owing
to its vital metabolic products and intermediates such as NADPH, ribose 5-phosphate etc …

Imidazole Carbamates as a Promising Alternative for Treating Trichomoniasis: In Vitro Effects on the Growth and Gene Expression of Trichomonas vaginalis

V Martínez-Rosas, G Navarrete-Vázquez… - Molecules, 2024 - mdpi.com
Metronidazole (MTZ) is the most common drug used against Trichomonas vaginalis (T.
vaginalis) infections; however, treatment failures and high rates of recurrence of …

Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of Giardia lamblia: Biochemical and In Silico Characterization of a New Druggable Target

V Martínez-Rosas, B Hernández-Ochoa… - International Journal of …, 2023 - mdpi.com
Giardiasis, which is caused by Giardia lamblia infection, is a relevant cause of morbidity and
mortality worldwide. Because no vaccines are currently available to treat giardiasis …