Zoonotic animal influenza virus and potential mixing vessel hosts

EM Abdelwhab, TC Mettenleiter - Viruses, 2023 - mdpi.com
Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-
stranded segmented RNA genome. They infect a wide range of animals, including humans …

Role of receptor binding specificity in influenza A virus transmission and pathogenesis

M de Graaf, RAM Fouchier - The EMBO journal, 2014 - embopress.org
The recent emergence of a novel avian A/H 7 N 9 influenza virus in poultry and humans in C
hina, as well as laboratory studies on adaptation and transmission of avian A/H 5 N 1 …

An overview of influenza A virus genes, protein functions, and replication cycle highlighting important updates

RP Chauhan, ML Gordon - Virus Genes, 2022 - Springer
The recent research findings on influenza A virus (IAV) genome biology prompted us to
present a comprehensive overview of IAV genes, protein functions, and replication cycle …

Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface

MI Nelson, AL Vincent - Trends in microbiology, 2015 - cell.com
The origins of the 2009 influenza A (H1N1) pandemic in swine are unknown, highlighting
gaps in our understanding of influenza A virus (IAV) ecology and evolution. We review how …

The interplay between the host receptor and influenza virus hemagglutinin and neuraminidase

L Byrd-Leotis, RD Cummings… - International journal of …, 2017 - mdpi.com
The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of influenza A virus are
responsible for the surface interactions of the virion with the host. Entry of the virus is …

[HTML][HTML] Surveillance of European domestic pig populations identifies an emerging reservoir of potentially zoonotic swine influenza A viruses

D Henritzi, PP Petric, NS Lewis, A Graaf, A Pessia… - Cell Host & Microbe, 2020 - cell.com
Swine influenza A viruses (swIAVs) can play a crucial role in the generation of new human
pandemic viruses. In this study, in-depth passive surveillance comprising nearly 2,500 …

Influence of host sialic acid receptors structure on the host specificity of influenza viruses

C Zhao, J Pu - Viruses, 2022 - mdpi.com
Influenza viruses need to use sialic acid receptors to invade host cells, and the α-2, 3 and α-
2, 6 sialic acids glycosidic bonds linking the terminal sialic acids are generally considered to …

[HTML][HTML] Transmission of influenza A viruses

G Neumann, Y Kawaoka - Virology, 2015 - Elsevier
Influenza A viruses cause respiratory infections that range from asymptomatic to deadly in
humans. Widespread outbreaks (pandemics) are attributable to 'novel'viruses that possess a …

[HTML][HTML] One health, multiple challenges: The inter-species transmission of influenza A virus

KR Short, M Richard, JH Verhagen, D van Riel… - One health, 2015 - Elsevier
Influenza A viruses are amongst the most challenging viruses that threaten both human and
animal health. Influenza A viruses are unique in many ways. Firstly, they are unique in the …

Influenza A virus in swine: epidemiology, challenges and vaccination strategies

JC Mancera Gracia, DS Pearce, A Masic… - Frontiers in Veterinary …, 2020 - frontiersin.org
Influenza A viruses cause acute respiratory infections in swine that result in significant
economic losses for global pig production. Currently, three different subtypes of influenza A …