[HTML][HTML] NADPH oxidases and ROS signaling in the gastrointestinal tract
Reactive oxygen species (ROS), initially categorized as toxic by-products of aerobic
metabolism, have often been called a double-edged sword. ROS are considered …
metabolism, have often been called a double-edged sword. ROS are considered …
The emerging role of lncRNAs in inflammatory bowel disease
Dysregulation of long noncoding RNA (lncRNA) expression is linked to the development of
various diseases. Recently, an emerging body of evidence has indicated that lncRNAs play …
various diseases. Recently, an emerging body of evidence has indicated that lncRNAs play …
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
WT Wang, H Ye, PP Wei, BW Han, B He… - Journal of hematology & …, 2016 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are known to play important roles in
different cell contexts, including cancers. However, little is known about lncRNAs in …
different cell contexts, including cancers. However, little is known about lncRNAs in …
Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation
A Paniri, H Akhavan-Niaki - Life sciences, 2020 - Elsevier
The world has witnessed a high morbidity and mortality caused by SARS-CoV-2, and global
death toll is still rising. Exaggerated inflammatory responses are thought to be more …
death toll is still rising. Exaggerated inflammatory responses are thought to be more …
New insights into the epigenetic regulation of inflammatory bowel disease
J Xu, H Xu, M Yang, Y Liang, Q Peng… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the colonic mucosa.
Environmental factors, genetics, intestinal microbiota, and the immune system are all …
Environmental factors, genetics, intestinal microbiota, and the immune system are all …
Disease-causing mutations and rearrangements in long non-coding RNA gene loci
M Aznaourova, N Schmerer, B Schmeck… - Frontiers in …, 2020 - frontiersin.org
The classic understanding of molecular disease-mechanisms is largely based on protein-
centric models. During the past decade however, genetic studies have identified numerous …
centric models. During the past decade however, genetic studies have identified numerous …
IPMiner: hidden ncRNA-protein interaction sequential pattern mining with stacked autoencoder for accurate computational prediction
Abstract Background Non-coding RNAs (ncRNAs) play crucial roles in many biological
processes, such as post-transcription of gene regulation. ncRNAs mainly function through …
processes, such as post-transcription of gene regulation. ncRNAs mainly function through …
The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis
This study reveals a previously uncharacterized mechanism to restrict intestinal
inflammation via a regulatory RNA transcribed from a noncoding genomic locus. We …
inflammation via a regulatory RNA transcribed from a noncoding genomic locus. We …
A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation
D Padua, S Mahurkar-Joshi, IKM Law… - American Journal …, 2016 - journals.physiology.org
High-throughput technologies revealed new categories of genes, including the long
noncoding RNAs (lncRNAs), involved in the pathogenesis of human disease; however, the …
noncoding RNAs (lncRNAs), involved in the pathogenesis of human disease; however, the …
The research progress of LncRNA involved in the regulation of inflammatory diseases
K Liao, J Xu, W Yang, X You, Q Zhong, X Wang - Molecular immunology, 2018 - Elsevier
Long non-coding RNA (lncRNA) is a non-coding RNA which lacks a complete open reading
frame (ORF) and plays an important role in biological processes such as cell proliferation …
frame (ORF) and plays an important role in biological processes such as cell proliferation …