Postdiagnosis body fatness, weight change and breast cancer prognosis: Global Cancer Update Program (CUP global) systematic literature review and meta‐analysis

DSM Chan, R Vieira, L Abar, D Aune… - … Journal of Cancer, 2023 - Wiley Online Library
Previous evidence on postdiagnosis body fatness and mortality after breast cancer was
graded as limited‐suggestive. To evaluate the evidence on body mass index (BMI), waist …

Mendelian randomization analysis revealed potential metabolic causal factors for breast cancer

M Zhou, M Henricks, V Loch, G Zhang, Y Lu, X Li - Scientific Reports, 2023 - nature.com
Observational studies showed that metabolic phenotypes were associated with the risk of
developing breast cancer (BC). However, those results are inconsistent regarding the …

Impact of BMI on the survival outcomes of non-small cell lung cancer patients treated with immune checkpoint inhibitors: a meta-analysis

T Zhang, S Li, J Chang, Y Qin, C Li - BMC cancer, 2023 - Springer
Objectives ICIs have become the standard treatment for advanced NSCLC patients.
Currently, PD-L1 is the most widely useful biomarker to predict ICI efficacy, but the sensitivity …

Causal pathways linking polycystic ovary syndrome to distinct breast cancer subtypes through mediator factors: a multivariable mendelian randomization analysis

R Cao, L Chen, Y Liu, X Wang, R Ma, Q Zhao… - Journal of Ovarian …, 2023 - Springer
Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by ovarian cysts,
high androgen levels, and irregular menstruation. The causality between PCOS and breast …

Body mass index and the risk of basal cell carcinoma: evidence from Mendelian randomization analysis

L Lu, B Wan, H Zeng, J Guo, M Li, M Sun - PeerJ, 2023 - peerj.com
Objective We aim to test whether body mass index (BMI) is causally associated with the risk
of basal cell carcinoma (BCC) using Mendelian randomization (MR) analysis. Methods …

Genetic evidence supporting the causal role of 25-hydroxyvitamin D levels in the prognosis of ER− breast cancer: A Mendelian randomization study

S Wu, XD Ma, XM Zhang, C Shi, KY Du, YJ Liu - Medicine, 2024 - journals.lww.com
This study aims to investigate the connection between 25-hydroxyvitamin D (25 (OH) D)
levels and the prognosis of breast cancer with various estrogen receptor (ER) statuses. The …

The causality between Type 2 diabetes and breast cancer: a bidirectional two-sample Mendelian randomization study

L Zhang, S Liu, G Yue, H Niu, M Hu, Y Zheng… - Future …, 2024 - Taylor & Francis
Objective: Observational studies showed that Type 2 diabetes increased the risk of breast
cancer, and vice versa. However, it is uncertain whether the link is causal or just due to …

使用孟德爾隨機化試驗針對歐洲英國族群與漢族, 探索去脂肪體重與全身脂肪重量對乳癌的因果關係

蔡佳宏 - 2022 - tdr.lib.ntu.edu.tw
背景: 乳癌為女性發生率首位的癌症, 其中之一的主要風險因子為肥胖, 肥胖的測量指標眾多,
然而在孟德爾隨機化試驗(Mendelian randomization, MR) 的文獻回顧中 …

The causal relationship of asthma to sarcopenia revealed by Mendelian randomization analysis and meta-analysis

H Xu, J Zhu, R Zhang, H Gou - 2024 - researchsquare.com
Objectives: Sarcopenia is age-related muscle loss that results in low hand grip strength, loss
of muscle weight and a slow walking speed. Asthma is recognized as a risk factor …

Sobrepeso, obesidad y cáncer de mama

J Mejia-Montilla, N Reyna-Villasmil… - Revista de Obstetricia y …, 2022 - saber.ucv.ve
La obesidad produce trastornos metabólicos e insuficiencia orgánica y aumenta el riesgo
de muchos tipos de cáncer. La posible relación entre obesidad y cáncer de mama depende …