Cyclin-dependent kinases (CDKs) are serine/threonine kinases whose catalytic activities are
regulated by interactions with cyclins and CDK inhibitors (CKIs). CDKs are key regulatory …

Flavonoids, commonly found in various plants, are a class of polyphenolic compounds
having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted …

Triple negative breast cancer (TNBC), which is typically lack of expression of estrogen
receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 …

The medicinal plant Scutellaria baicalensis, commonly known as Chinese skullcap or
Huang‐Qin, has been used as a traditional medicine for several thousand years. The roots …

Presently, breast cancer (BC) is one of the most common malignancies diagnosed and the
leading cause of tumor-related deaths among women worldwide. Cell cycle dysregulation is …

Background The most common and deadly cancer in female is breast cancer (BC) and new
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …

Wogonin is a flavonoid found in different plants such as roots of Scutellaria baicalensis
Georgi distributed mainly in Asia and Europe. Dried root extracts of S. baicalensis with high …

Cancer cell plasticity plays a crucial role in tumor initiation, progression, and metastasis and
is implicated in the multiple cancer defense mechanisms associated with therapy resistance …

Glioblastoma multiforme (GBM) is the most aggressive and lethal primary brain tumor whose
median survival is less than 15 months. The current treatment regimen comprising surgical …

Triple-negative breast cancer (TNBC) is the most aggressive type of cancer, with a high risk
of death on recurrence. To date, there is a lack of approved targeted agents for the treatment …