Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

The involvement of the prostaglandin E2 (PGE2) system in cancer progression has long
been recognized. PGE2 functions as an autocrine and paracrine signaling molecule with …

While fundamental in their innate role in combating infection and responding to injury,
neutrophils are emerging as key modulators of adaptive immune responses. Such functions …

Neutrophils are the first immune cells to reach inflamed sites and contribute to the
pathogenesis of chronic inflammatory skin diseases. Yet, little is known about the pattern of …

Neutrophils are the most abundant immune cell in the circulation of human and act as
gatekeepers to discard foreign elements that have entered the body. They are essential in …

Simple Summary Non-melanoma skin cancers, including basal cell carcinoma and
squamous cell carcinoma, are the most common types of cancer in the United States. In …

NK cells and tissue-resident innate lymphoid cells (ILCs) are innate effectors found in the
skin. To investigate their temporal dynamics and specific functions throughout the …

Simple Summary The tumor is a complex system that is composed of tumor cells,
themselves surrounded by many other different cell types. Among these cells, myeloid cells …

Simple Summary Cutaneous squamous cell carcinoma (cSCC) is the second most common
form of skin cancer worldwide. Due to its high mutational burden, cSCC remains poorly …

Simple Summary Cutaneous squamous cell carcinoma (cSCC) is a complex disease arising
from an interplay of UV-induced DNA damage, genetic mutations, and alterations in the …